Overview
- Features ?comprehensive and systematic analysis of biological and therapeutic targets associated with intra-tumor hypoxia
- Focuses on translational aspects associated with intra-tumor hypoxia
- Explores the opportunities for drug development offered by this unique feature of the tumor microenvironments
- Includes supplementary material: sn.pub/extras
Part of the book series: Cancer Drug Discovery and Development (CDD&D)
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Table of contents (15 chapters)
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Imaging
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Therapy
Keywords
About this book
This volume will cover the latest research and translational aspects associated with intra-tumor hypoxia, along with opportunities for drug development offered by this unique feature of the tumor microenvironment. The ongoing efforts to translate our understanding of the biology underlying intra-tumor hypoxia in viable therapeutic options face many challenges, but this book will provide an opportunity for an in-depth analysis of the fundamental mechanisms implicated in the adaption to low oxygen levels and will scrutinize the potential for opportunities that are being pursued in both research and the drug development industry.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Hypoxia and Cancer
Book Subtitle: Biological Implications and Therapeutic Opportunities
Editors: Giovanni Melillo
Series Title: Cancer Drug Discovery and Development
DOI: https://doi.org/10.1007/978-1-4614-9167-5
Publisher: Humana New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media New York 2014
Hardcover ISBN: 978-1-4614-9166-8Published: 10 November 2013
Softcover ISBN: 978-1-4939-5355-4Published: 23 August 2016
eBook ISBN: 978-1-4614-9167-5Published: 09 November 2013
Series ISSN: 2196-9906
Series E-ISSN: 2196-9914
Edition Number: 1
Number of Pages: XIV, 363
Number of Illustrations: 17 b/w illustrations, 36 illustrations in colour
Topics: Cancer Research, Molecular Medicine, Pharmacology/Toxicology, Stem Cells