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The Nucleolus

  • Book
  • © 2011

Overview

Editors:
  1. Mark O. J. Olson

    1. Dept. Biochemistry, University of Mississippi Medical Center, Jackson, USA

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  • Covers recent discoveries on novel functions of the nucleolus.
  • Emphasizes nucleolar proteins while also including the crucial importance of nucleic acids.
  • Includes chapters on nucleolar ultrastructure, the locations and dynamics of nucleolar components, and on regulatory systems.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Protein Reviews (PRON, volume 15)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xxv
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  2. Nucleolar Structure and Organization

    1. Front Matter

      Pages 1-1
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    2. Structural Organization of the Nucleolus as a Consequence of the Dynamics of Ribosome Biogenesis

      • Danièle Hernandez-Verdun
      Pages 3-28

    3. The Dynamic Proteome of the Nucleolus

      • François-Michel Boisvert, Yasmeen Ahmad, Angus I. Lamond
      Pages 29-42

    4. The Structure of rDNA Chromatin

      • Peter J. Shaw, Peter C. McKeown
      Pages 43-55

    5. The Epigenetics of the Nucleolus: Structure and Function of Active and Silent Ribosomal RNA Genes

      • Raffaella Santoro
      Pages 57-82

    6. UBF an Essential Player in Maintenance of Active NORs and Nucleolar Formation

      • Alice Grob, Christine Colleran, Brian McStay
      Pages 83-103

  3. Role of the Nucleolus in Ribosome Biogenesis

    1. Front Matter

      Pages 105-105
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    2. The RNA Polymerase I Transcription Machinery

      • Renate Voit, Ingrid Grummt
      Pages 107-134

    3. Small Ribonucleoproteins in Ribosome Biogenesis

      • Franziska Bleichert, Susan Baserga
      Pages 135-156

    4. Crosstalk Between Ribosome Synthesis and Cell Cycle Progression and Its Potential Implications in Human Diseases

      • Marie Gérus, Michèle Caizergues-Ferrer, Yves Henry, Anthony Henras
      Pages 157-184

    5. The Multiple Properties and Functions of Nucleolin

      • Rong Cong, Sadhan Das, Philippe Bouvet
      Pages 185-212

    6. The Multifunctional Nucleolar Protein Nucleophosmin/NPM/B23 and the Nucleoplasmin Family of Proteins

      • Shea Ping Yip, Parco M. Siu, Polly H. M. Leung, Yanxiang Zhao, Benjamin Y. M. Yung
      Pages 213-252

    7. Structure and Function of Nopp140 and Treacle

      • Fang He, Patrick DiMario
      Pages 253-278

  4. Novel Functions of the Nucleolus

    1. Front Matter

      Pages 279-279
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    2. The Role of the Nucleolus in the Stress Response

      • Laura A. Tollini, Rebecca A. Frum, Yanping Zhang
      Pages 281-299

    3. New Frontiers in Nucleolar Research: Nucleostemin and Related Proteins

      • Robert Y. L. Tsai
      Pages 301-320

    4. Viruses and the Nucleolus

      • David Matthews, Edward Emmott, Julian Hiscox
      Pages 321-345

    5. Assembly of Signal Recognition Particles in the Nucleolus

      • Marty R. Jacobson
      Pages 347-360

    6. Relationship of the Cajal Body to the Nucleolus

      • Andrew Gilder, Michael Hebert
      Pages 361-380
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About this book

Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.

Editors and Affiliations

  • Dept. Biochemistry, University of Mississippi Medical Center, Jackson, USA

    Mark O. J. Olson

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