Overview
Part of the book series: Developments in Molecular and Cellular Biochemistry (DMCB, volume 39)
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Table of contents(23 chapters)
About this book
Recognition of activated or modified signaling molecules by specific antibodies, new selective inhibitors, and fluorescent fusion tags are but a few of the tools used to dissect signaling pathways and cross-talk mechanisms that may eventually allow rational drug design. Understanding the regulation of cardiac hypertrophy in all its complexity remains a fundamental goal of cardiac research. Since the advancement of adenovirally mediated gene transfer, transfection efficiency is no longer a limiting factor in the study of cardiomyocytes. A limiting factor in considering cell transplantion as a strategy to repair the damaged heart is cell availability at the right time. Cardiac gap junctions, intercellular communication channels that allow electrical and metabolic coupling and play an important role in arrhythmogenesis are now understood to be exquisite sensors of cardiac change.
The reports in this volume incLude elegant studies that made use of cutting edge technological advances and many specialized reagents to address these issues.
Editors and Affiliations
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Institute of Cardiovascular Sciences, St. Boniface General Hospital Research Centre, Faculty of Medicine, University of Manitoba, Winnipeg, Canada
Elissavet Kardami, Larry Hryshko
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Institute of Cardiovascular Sciences and Division of Stroke and Vascular Disease, St. Boniface General Hospital Research Centre and Department of Physiology, University of Manitoba, Winnipeg, Canada
Nasrin Mesaeli
Bibliographic Information
Book Title: Cardiac Cell Biology
Editors: Elissavet Kardami, Larry Hryshko, Nasrin Mesaeli
Series Title: Developments in Molecular and Cellular Biochemistry
DOI: https://doi.org/10.1007/978-1-4757-4712-6
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 2003
Hardcover ISBN: 978-1-4020-7296-3Published: 28 February 2003
Softcover ISBN: 978-1-4419-5324-7Published: 03 December 2010
eBook ISBN: 978-1-4757-4712-6Published: 29 June 2013
Edition Number: 1
Number of Pages: V, 194
Number of Illustrations: 179 b/w illustrations, 40 illustrations in colour
Topics: Biochemistry, general, Human Physiology