Editors:
- Unique and novel enzyme whose physiological/ pathological function(s) just start to be revealed
- Up to date information by invited speakers at September 2nd International Conference on Paraoxonases
- Chapters by the leading international experts in their field
- Covers the breadth of current research into the paraoxonases
Part of the book series: Proteins and Cell Regulation (PROR, volume 6)
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Table of contents (21 chapters)
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Front Matter
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The Bert La Du Memorial Lecture
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Front Matter
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PONs and Atherosclerosis
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Front Matter
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PONs in Disease other than Atherosclerosis
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Front Matter
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PON and Toxicology
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Front Matter
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About this book
Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years. Before this time only PON1 was known and research was restricted to toxicologists investigating the metabolism of organophosphate insecticides and nerve gases and a few “mad” scientists searching for “natural” substrates.
Since this time two new members PON2 and PON3 have been discovered, all 3 PONs have been shown to act as antioxidants and the PON family has taken centre stage as major players in the development of a wide variety of diseases such as cardiovascular disease, diabetes mellitus, rheumatism, Alzheimer and many more while remaining important in determining organophosphate toxicity.
In September 2006 the 2nd International Conference on Paraoxonases took place in Hajdúszoboszló, Hungary, bringing together the world's foremost experts in the field. The current book is a distillation of the plenary lectures which took place at the meeting, resulting in a comprehensive up to date, state of the art review of current paraoxonase research.
Editors and Affiliations
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University of Manchester, U.K
Bharti Mackness, Mike Mackness
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Technion Faculty of Medicine, Haifa, Israel
Michael Aviram
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University of Debrecen, Hungary
György Paragh
Bibliographic Information
Book Title: The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism
Editors: Bharti Mackness, Mike Mackness, Michael Aviram, György Paragh
Series Title: Proteins and Cell Regulation
DOI: https://doi.org/10.1007/978-1-4020-6561-3
Publisher: Springer Dordrecht
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media B.V. 2008
Hardcover ISBN: 978-1-4020-6560-6Published: 14 November 2007
Softcover ISBN: 978-90-481-7670-0Published: 25 November 2010
eBook ISBN: 978-1-4020-6561-3Published: 26 October 2007
Series ISSN: 1567-2530
Series E-ISSN: 2542-9973
Edition Number: 1
Number of Pages: XV, 325
Topics: Internal Medicine, Cardiology, Diabetes, Metabolic Diseases, Medical Biochemistry