Overview
- Editors:
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Leopold Flohé
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MOLISA GmbH Magdeburg, Magdeburg, Germany
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J. Robin Harris
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University of Mainz, Mainz, Germany
- First authoritative compilation in book form on the peroxiredoxins
- Chapters contributed by top experts in their field of study
- Contains a broad survey of all significant aspects of the peroxiredoxins
- For the first time the book brings clarity into a field that, for historical reasons, has so far been extremely confused
- Links the emerging field to related topics of biochemistry and physiology
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Table of contents (18 chapters)
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- Leopold Flohé, J. Robin Harris
Pages 1-25
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- Bernard Knoops, ElÉonore Loumaye, ValÉrie Van Der Eecken
Pages 27-40
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- P. Andrew Karplus, Andrea Hall
Pages 41-60
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- Madia Trujillo, Gerardo Ferrer-Sueta, Leonor Thomson, Leopold Flohé, Rafael Radi
Pages 83-113
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- Thomas J. Jönsson, W. Todd Lowther
Pages 115-141
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- James M. Dubbs, Skorn Mongkolsuk
Pages 143-193
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- Marcel Deponte, Stefan Rahlfs, Katja Becker
Pages 219-229
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- Luise R. Krauth-Siegel, Marcelo A. Comini, Tanja Schlecker
Pages 231-251
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- Brian A. Morgan, Elizabeth A. Veal
Pages 253-265
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- Zhenbo Cao, J. Gordon Lindsay, Neil W. Isaacs
Pages 295-315
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- Bruno Schremmer, Yefim Manevich, Sheldon I. Feinstein, Aron B. Fisher
Pages 317-344
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- Isabelle Donnay, Bernard Knoops
Pages 345-355
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- Fumiyuki Hattori, Shinzo Oikawa
Pages 357-374
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- Tetsuro Ishii, Toru Yanagawa
Pages 375-384
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Back Matter
Pages 385-389
About this book
A volume within the Subcellular Biochemistry series is an appropriate setting for the first multi-author book devoted to the new family of antioxidant and cell signalling proteins, the peroxiredoxins. Within the antioxidant and cell signalling fields, even the existence of the peroxiredoxins has yet to be appreciated by many; with this book we aim to rectify this situation. We have tried to select diverse chapter topics to cover relevant aspects of the subject and to persuade knowledgeable authors to contribute a manuscript. As almost inevitable, a few authors let us down by failing to respond, others could not submit a manuscript in time for personal reasons. These unfortunately were two of the pioneers, Earl Stadtman and Sue Goo Rhee, but we appreciate that they communicated a lot of details that helped us to reconstruct the early phase of peroxiredoxin enzymology. We have thus compiled a book that competently covers the peroxiredoxin field from its beginnings through to currently relevant topics. In the introductory Chapter 1 we provide a short historical survey of the subject, based upon the early structural and enzymic studies on peroxiredoxins, and then lead into some of our current personal interests, such as the likely continuing contribution of transmission electron microscopy (TEM) for the study of high molecular mass peroxiredoxin complexes and the association of peroxiredoxins with other proteins, and the targeting of drugs against microbial peroxiredoxins, as future therapeutic approaches.
Editors and Affiliations
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MOLISA GmbH Magdeburg, Magdeburg, Germany
Leopold Flohé
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University of Mainz, Mainz, Germany
J. Robin Harris