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Table of contents (13 chapters)
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The Vascular Wall under Physiological Conditions
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The Vascular Wall under Pathological Conditions
Keywords
About this book
Cell biology and molecular genetic studies have now identified an array of molecules elaborated by endothelial cells and vascular smooth muscle cells and by the blood-borne elements which interact with artery cells, defending the artery against injury and modulating evolving abnormal processes. Molecules which induce or inhibit endothelial and/or smooth muscle cells are currently under great scrutiny. Angiogenesis, which plays a major role in tumor growth, but may also be beneficial as a healing process in muscle ischemia, is discussed.
Apoptosis, or programmed cell death, has only recently been recognized as an essential process in blood vessel modeling and remodeling. An overview of apoptosis in the vascular system is presented.
It is increasingly evident that the adjustments of the blood vessel wall are made in the presence of deforming disease processes such as hypertension and atherosclerosis.
The second part of the book is concerned with the blood vessel wall in disease conditions. Several chapters review the role of the vessel and vascular cells in inflammation, and vascular remodeling during arterial hypertension and aging. One chapter is devoted to atherogenesis, atheroma and plaque instability, followed by the pathophysiology of post-angioplasty restenosis, which is a crucial issue in modern interventional cardiology.
Reviews
Journal of Vascular Surgery, 32:2 (2000)
Editors and Affiliations
Bibliographic Information
Book Title: Biology of the Arterial Wall
Editors: Bernard I. Levy, Alain Tedgui
Series Title: Basic Science for the Cardiologist
DOI: https://doi.org/10.1007/b102335
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1999
Hardcover ISBN: 978-0-7923-8458-8Published: 28 February 1999
Softcover ISBN: 978-1-4757-8269-1Published: 24 March 2013
eBook ISBN: 978-0-585-38146-6Published: 23 November 2007
Series ISSN: 1566-0753
Edition Number: 1
Number of Pages: XIV, 278
Topics: Human Physiology, Cardiology