Overview
- Editors:
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Arthur E. Baue
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Department of Surgery, St. Louis University Hospital, St. Louis, USA
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Eugen Faist
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Department of Surgery, Klinikum Grosshadern, University of Munich, Munich, Germany
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Donald E. Fry
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Department of Surgery, School of Medicine, University of New Mexico, New Mexico, USA
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Table of contents (73 chapters)
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Front Matter
Pages i-xxii
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Development of SIRS, MODS, and MOF
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- Patrick J. Offner, Ernest E. Moore
Pages 30-43
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- Philip S. Barie, Lynn J. Hydo
Pages 52-67
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Mechanisms of SIRS and Organ Failure
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- E. E. de Bel, R. J. A. Goris
Pages 71-81
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- Matthias Majetschak, Christian Waydhas
Pages 101-107
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- Alexander Shnyra, Michael Luchi, Jiangjun Gao, Christopher J. Papasian, David L. Horn, Richard Silverstein et al.
Pages 114-130
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- Eugen Faist, Martin K. Angele
Pages 134-142
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Mediators and Effectors
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Front Matter
Pages 143-143
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- Lyle L. Moldawer, Rebecca M. Minter, John E. Rectenwald III
Pages 145-154
About this book
Inflammation in itself is not to be considered as a disease . . . and in disease, where it can alter the diseased mode of action, it likewise leads to a cure; but where it cannot accomplish that solitary purpose . . . it does mischief - John Hunter, A Treatise on the Blood, ITfIlammation, and Gunshot Woundr (London, 1794)1 As we reached the millennium, we recognized the gap between our scientific knowledge of biologic processes and our more limited clinical capabilities in the care of patients. Our science is strong. Molecular biology is powerful, but our therapy to help patients is weaker and more limited. For this reason, this book focuses on the problems of multiple organ failure (MOF), multiple organ dysfunction syndrome (MODS), and systemic inflammatory response syndrome is, patients who have severe injuries; require major, (SIRS) in high-risk patients, that overwhelming operations; or have serious illnesses requiring intensive care; patients who have diseases elsewhere, in other organs or systems, that limit their capabilities to survive a new insult; and patients who are elderly or at high risk for sepsis or other complications. These are the patients who need our help. They need the advances in science, in molecular biology, immunology, pathophysiology, biochemistry, genetics, high technology, and other areas of maximum support at the bedside. These advances could potentially have the greatest impact on improving patient care.
Reviews
"As multiple organ dysfunction remains the significant cause of ICU mortality, this textbook, the leading secondary source on this problem, is an important contribution." Doody's Reviews
Editors and Affiliations
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Department of Surgery, St. Louis University Hospital, St. Louis, USA
Arthur E. Baue
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Department of Surgery, Klinikum Grosshadern, University of Munich, Munich, Germany
Eugen Faist
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Department of Surgery, School of Medicine, University of New Mexico, New Mexico, USA
Donald E. Fry
