Overview
- Most up-to-date and comprehensive volume on lysosomal storage diseases available
- Chapters written by leading experts in the field
- Features chapters summaries and detailed illustrations
Part of the book series: Medical Intelligence Unit (MIUN)
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Table of contents (15 chapters)
Keywords
About this book
Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment.
This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases. In addition to these classical topics, new insights into lysosomal functions are covered by chapters dealing with specialized lysosomes involved in bone resorption and plasma membrane repair, the lysosomal transciptome, and proteome and the emerging role of lysosomes in special forms of autophagy.
This book will provide readers with a comprehensive overview into how this fascinating organelle works and how research in the field is developing.
Authors and Affiliations
Bibliographic Information
Book Title: Lysosomes
Authors: Paul Saftig
Series Title: Medical Intelligence Unit
DOI: https://doi.org/10.1007/0-387-28957-7
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag US 2005
Hardcover ISBN: 978-0-387-25562-0Published: 03 August 2005
Softcover ISBN: 978-1-4419-3804-6Published: 16 December 2010
eBook ISBN: 978-0-387-28957-1Published: 20 March 2007
Edition Number: 1
Number of Pages: XII, 197
Topics: Cell Biology, Biochemistry, general, Human Genetics, Neurosciences