Advances in Hemostasis and Thrombosis

1. Front Matter

   Pages i-x

   PDF

2. Hemostasis: A Review

   • Angelo Baserga

   Pages 1-5

3. Platelets, Endothelium and Vessel Injury

   • J. F. Mustard

   Pages 7-16

4. Roles of Thrombospondin and Fibronectin in Vascular Injury

   • Deane F. Mosher, Paula J. McKeown-Longo

   Pages 17-26

5. The Interaction of Fibronectin, Endothelium, and Subendothelium

   • Franco Piovella

   Pages 27-40

6. Platelets and the Platelet-Derived Growth Factor in the Pathogenesis of Atherosclerosis

   • Russell Ross

   Pages 41-49

7. Monoclonal Antibodies to Human von Willebrand Factor Study of its Structure-Function Relationship

   • Dominique Meyer

   Pages 51-58

8. The Membrane Glycoproteins: Adhesion and Aggregation of Platelets

   • Edoardo Ascari, Carlo L. Balduini, Fabiola Sinigaglia, Cesare Balduini

   Pages 59-74

9. The Changes in Arachidonic Acid Metabolism in Ischemic Heart Disease — Their Pathophysiological Consequences

   • G. G. Neri Serneri

   Pages 75-77

10. Hemorheology and Thrombosis

    • J. Dormandy

    Pages 79-91

11. Blood Cells and Thrombosis: The Rheology and Activation of the Coagulative Process

    • Tullio Di Perri

    Pages 93-102

12. Procoagulant Activity of Platelets, Leukocytes, and Cancer Cells Possible Role in Hemostasis and Thrombosis

    • Nicola Semeraro

    Pages 103-115

13. Antithrombin III and Other Natural Inhibitors of Coagulation

    • Tiziano Barbui, Guido Finazzi

    Pages 117-128

14. On the Evaluation of the Thrombotic Risk

    • G. Mariani, G. D. Di Nucci, A. Chistolini, M. Motta, F. Mandelli

    Pages 129-140

15. The Correlation Between Fatty Acids and Platelet Function

    • E. Cacciola, R. Musso, R. Giustolisi, N. M. Catania, E. Cacciola, R. R. Cacciola

    Pages 141-148

16. Protein C — An Inhibitor of Blood Coagulation: Biochemistry, Physiology, Clinical Aspects

    • P. M. Mannucci, S. Viganò, S. Antoncecchi, N. Ciavarella

    Pages 149-157

17. Immune Complexes and Thrombosis

    • G. Camussi, F. Gavosto

    Pages 159-171

18. Hemostatic Parameters and Ischemic Heart Disease

    • M. Cortellaro, C. Boschetti, G. Moreo, V. Antoniazzi

    Pages 173-190

19. Critical Review of Myocardial Infarction Prevention with Antiaggregants

    • E. E. Polli, M. Cortellaro

    Pages 191-205

20. Hemostatic Alterations in Diabetes Mellitus

    • Gian Franco Gensini

    Pages 207-212

A greater knowledge of the basic molecular mechanisms which regulate platelet function, coagulation, the fibrinolytic system and their interaction with the vessel wall has allowed a better understanding of the numerous aspects involved in the pathogenesis of thrombosis and the regulation of hemostasis. Thrombosis represents today one of the causes of death in the Western hemisphere. Arterial thrombosis may lead to myocardial infarction, cerebral and peripheral vascular diseases. Venous thrombosis, on the other hand, is a complication of heart disease, surgery, extensive trauma, several obstetric pathologies, and may, at times, develop in apparently healthy subjects. These complex problems are dealt with within the content of "Advances in Hemostasis and Thrombosis." The present papers contain up-to-date information on hemostasis, the role of prostaglandins, fibrinolytic coagulation, rheology, and modern therapeutic approaches along with their clinical application. This book, therefore, offers the reader the opportunity to profit from a rare encounter, an interdisciplinary cooperation, with scientific contributions from numerous countries.

• blood
• diabetes
• metabolism
• rheology
• thrombosis

• University of Palermo, Palermo, Italy

  A. Cajozzo, R. Perricone, P. Marco, P. Palazzolo

Policies and ethics