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Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry

  • Book
  • © 2016

Overview

  • Showcases new techniques and applications in MALDI MS
  • Demonstrates how MALDI is preferable to ESI (Electrospray ionization)
  • Includes the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas such as cancer proteomics

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Table of contents (14 chapters)

  1. Fundamental Improvements in MALDI

  2. Applications of Liquid MALDI Mass Spectrometry

  3. Advances in MALDI Mass Spectrometry Imaging

  4. MS Profiling of Clinical Samples

  5. MALDI Biotyping Beyond the Clinic

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About this book

This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences.

This book also:

• Showcases new techniques and applications in MALDI MS

• Demonstrates how MALDI is preferable to ESI (electrospray ionization)

• Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics

Editors and Affiliations

  • Department of Chemistry, University of Reading, Reading, United Kingdom

    Rainer Cramer

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