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Growth Factors and their Receptors in Cancer Metastasis

  • Book
  • © 2001

Overview

Editors:
  1. C. R. Snyder

    1. University of Kansas, Lawrence

  2. Wen G. Jiang

    1. University of Wales College of Medicine, Cardiff, UK

  3. Kunio Matsumoto

    1. University of Osaka Medical School, Osaka, Japan

  4. Toshikazu Nakamura

    1. University of Osaka Medical School, Osaka, Japan

Part of the book series: Cancer Metastasis - Biology and Treatment (CMBT, volume 2)

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About this book

about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth and differentiation factors seem to The family of growth factors regulate many processes in human disease consists of more than thirty members in and, in particular, tumor development. humans alone (15, 16). They cluster in Our understanding of how two major groups, the group composed of initiated signals are mediated has both the bone morphogenetic proteins increased dramatically in the last fifteen (BMP) and growth and differentiation years. Firstly, the prototype of factors (GDFs), and the group formed by this still constantly growing family, was the Activins, and Nodals. The two identified and cloned (1). Secondly, the groups differ in their use of receptors for family receptors were transmembrane receptors and the identified by expression cloning from subsequent activation of the mammalian tissue culture (2-7). Thirdly, transcriptional mediators (for recent genetic screens in Drosophila reviews see (13, 14, 17)).

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. The Role of Leukemia Inhibitory Factor in Cancer and Cancer Metastasis

    • Farhad Ravandi, Zeev Estrov
    Pages 1-25

  3. Interleukin-2 and its Receptors in Human Solid Tumours: Immunobiology and Clinical Significance

    • Theresa L. Whiteside, Torsten E. Reichert, Qing Ping Dou
    Pages 27-50

  4. Interleukin-8 and Angiogenesis

    • Tracey A. Martin
    Pages 51-65

  5. The Role of Interleukein-11 in the Formation of Bone Metastases

    • Naoya Fujita, Takashi Tsuruo
    Pages 67-78

  6. Therapeutic Potential of Adenovirus Mediated Interleukin-12 Gene Therapy for Prostate Cancer

    • Shin Ebara, Yasutomo Nasu, Takefumi Satoh, Satoru Shimura, Chris H. Bangma, Gerald W. Hull et al.
    Pages 79-91

  7. Fibroblast Growth Factors and Their Receptors in Metastases of Prostate and Other Urological Cancers

    • Zoran Culig, Marcus V. Cronauer, Alfred Hobisch, Georg Bartsch, Helmut Klocker
    Pages 93-106

  8. Insulin-like Growth Factor Axis Elements in Breast Cancer Progression

    • Emilia Mira, Rosa Ana Lacalle, Carlos Martínez-A, Santos Mañes
    Pages 107-166

  9. The Role of Platelet Derived Growth Factor (PDGF) and Its Receptors in Cancer and Metastasis

    • Sara Weiss Feigelson, Cheryl Fitzer-Attas, Lea Eisenbach
    Pages 167-186

  10. TGFβ Receptor Signaling in Cancer and Metastasis

    • Martin Oft
    Pages 187-222

  11. VEGF-C/VEGFRS and Cancer Metastasis

    • Yutaka Yonemura, Yoshio Endou, Takuma Sasaki, Kazuo Sugiyama, Tetumouri Yamashima, Taina Partaneri et al.
    Pages 223-239

  12. HGF-c-Met Receptor Pathway in Tumor Invasion-metastasis and Potential Cancer Treatment With NK4

    • Kunio Matsumoto, Toshikazu Nakamura
    Pages 241-276

  13. Growth Factor Receptors and Cell Adhesion Complexes in Cytoskeletal Assembly/Anchorage

    • Gaynor Davies, Malcolm D. Mason, Wen G. Jiang
    Pages 277-290

  14. Back Matter

    Pages 291-303
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Editors and Affiliations

  • University of Kansas, Lawrence

    C. R. Snyder

  • University of Wales College of Medicine, Cardiff, UK

    Wen G. Jiang

  • University of Osaka Medical School, Osaka, Japan

    Kunio Matsumoto, Toshikazu Nakamura

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Bibliographic Information

  • Book Title: Growth Factors and their Receptors in Cancer Metastasis

  • Editors: C. R. Snyder, Wen G. Jiang, Kunio Matsumoto, Toshikazu Nakamura

  • Series Title: Cancer Metastasis - Biology and Treatment

  • DOI: https://doi.org/10.1007/0-306-48399-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 2001

  • Hardcover ISBN: 978-0-7923-7141-0Published: 31 October 2001

  • Softcover ISBN: 978-90-481-5757-0Published: 05 December 2010

  • eBook ISBN: 978-0-306-48399-8Published: 11 April 2006

  • Series ISSN: 1568-2102

  • Series E-ISSN: 2215-1648

  • Edition Number: 1

  • Number of Pages: X, 303

  • Number of Illustrations: 51 b/w illustrations, 16 illustrations in colour

  • Topics: Cancer Research, Oncology, Pathology

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