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Orexin and Sleep

Molecular, Functional and Clinical Aspects

Editors: Sakurai, Takeshi, Pandi-Perumal, S.R., Monti, Jaime M. (Eds.)

  • Provides comprehensive overview of the field, in-depth coverage of basic and clinical research
  • Presents established theories as well as the most recent developments in neurology, psychiatry, neuroendocrinology, neuroanatomy, neuropharmacology, and molecular biology
  • Shares highly applicable knowledge for sleep research and clinical practice, with proven strategies for difficult-to-treat patients with narcolepsy and comorbid mental disturbances
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Buy this book

eBook 118,99 €
price for France (gross)
  • ISBN 978-3-319-23078-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 147,69 €
price for France (gross)
  • ISBN 978-3-319-23077-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume is intended for neuropharmacologists, psychopharmacologists, pharmacologists, pharmacists, sleep researchers, translational neuroscience researchers, and other basic researchers and clinical scientists interested in an interdisciplinary approach to sleep medicine. The level of the book is aiming at CNS researchers, drug development scientists, basic and clinical sleep researchers, as well as senior medical students and fellows in psychiatry and neurology. Orexin and Sleep provides a unique resource, giving a comprehensive and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular.

About the authors

Takeshi Sakurai, MD, PhD

Takeshi Sakurai is a professor in the Department of Molecular Neuroscience and Integrative Physiology, Faculty of Medicine, Kanazawa University (Japan). He obtained his M.D. and Ph.D. from the University of Tsukuba and received his postdoctoral training at the Howard Hughes Medical Institute at the University of Texas Southwestern Medical Center, Dallas, USA. The goal of his work is to identify novel neuropeptides and define their physiological roles. He is especially interested in neuropeptides involved in homeostatic processes and innate behaviors such as feeding, autonomic function, emotion, and sleep and wakefulness states. In recent years, he has focused on identifying the input and output systems of orexin neurons to reveal the neuronal network that plays an important role in regulating  sleep and wakefulness states.

S.R. Pandi-Perumal, MSc.,

Pandi-Perumal is the President and Chief Executive Officer of Somnogen Canada Inc, a Canadian Corporation. He is a well-recognized sleep researcher both nationally and internationally, and has authored many publications. His general area of research interest includes sleep and biological rhythms. He is a well-known editor in the field of sleep medicine and has edited over 20 volumes dealing with various sleep-related topics. He had an honorable mention in the New York Times in 2004. India International Friendship Society awarded 'Bharat Gaurav award' on January 12, 2013.

Jaime M. Monti, MD

Jaime M. Monti has obtained his MD from Uruguay and subsequently he had his early career trainings at Stanford University and National Institutes of Mental Health. He is a member of the International College of Neuropsychopharmacology, the Sleep Research Society (USA), the European Sleep Research Society, and the Argentinian Society of Sleep Medicine. Contributed

and served at various capacities in these societies. He has published over 150 peer-reviewed scientific papers and he has edited several volumes related to sleep. Over the years, he has won several prestigious awards for his research, including the Claude Bernard Award (Clinical Sleep Research) from the Government of France, and the Schering Award for Basic Sleep Research, in Germany.

Reviews

“This is an up-to-date look at these hypothalamic neuropeptides and how we have come to understand their wide range of neuroregulatory roles. … This is highly technical book that reviews in detail the research that has led to the discovery and understanding of the orexin neuropeptides and their role in a wide range of neuromodulatory systems. … provide some insights into how manipulation of this system may result in therapeutic interventions for a number of neurological and psychiatric conditions.” (Michael Easton, Doody’s Book Reviews, February, 2016)


Table of contents (22 chapters)

  • History of Orexin Research

    Sakurai, Takeshi

    Pages 1-25

    Preview Buy Chapter 29,94 €
  • The Hypocretin Story

    Lecea, Luis

    Pages 27-35

    Preview Buy Chapter 29,94 €
  • Input and Output Systems of Orexin Neurons

    Mochizuki, Takatoshi (et al.)

    Pages 37-52

    Preview Buy Chapter 29,94 €
  • Physiological Roles of Orexin Receptors on Sleep/Wakefulness Regulation

    Mieda, Michihiro (et al.)

    Pages 53-65

    Preview Buy Chapter 29,94 €
  • Orexin Receptor Functions in the Ascending Arousal System

    Leonard, Christopher S. (et al.)

    Pages 67-80

    Preview Buy Chapter 29,94 €

Buy this book

eBook 118,99 €
price for France (gross)
  • ISBN 978-3-319-23078-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 147,69 €
price for France (gross)
  • ISBN 978-3-319-23077-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Orexin and Sleep
Book Subtitle
Molecular, Functional and Clinical Aspects
Editors
  • Takeshi Sakurai
  • S.R. Pandi-Perumal
  • Jaime M. Monti
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-23078-8
DOI
10.1007/978-3-319-23078-8
Hardcover ISBN
978-3-319-23077-1
Edition Number
1
Number of Pages
XIV, 410
Topics