Advances in Nutritional Research Volume 10

1. Front Matter

   Pages i-xxix

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2. Introduction

   1. Front Matter

      Pages 1-1

      PDF

   2. Overview of the Mammalian Immune System

      • A. J. Husband

      Pages 3-14

   3. The Immunological System in Human Milk: The Past—A Pathway to the Future

      • Armond S. Goldman

      Pages 15-37

   4. Immunological Activities Associated with Milk

      • Shannon L. Kelleher, Bo Lönnerdal

      Pages 39-65

3. Milk and Risk of Infection During the Suckling Period

   1. Front Matter

      Pages 67-67

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   2. Breast Milk and the Risk of Opportunistic Infection in Infancy in Industrialized and Non-Industrialized Settings

      • Patrick F. W. Chien, Peter W. Howie

      Pages 69-104

   3. Breast Milk Transmission of Viral Disease

      • E. Richard Stiehm, Margaret A. Keller

      Pages 105-122

   4. Breast Milk Decreases the Risk of Neonatal Necrotizing Enterocolitis

      • Ann M. Kosloske

      Pages 123-137

   5. The Protective Properties of Milk and Colostrum in Non-Human Species

      • Ian Tizard

      Pages 139-166

   6. Mammary Gland Defense: The Role of Colostrum, Milk and Involution Secretion

      • Catherine M. Fetherston, Chee Seong Lee, Peter E. Hartmann

      Pages 167-198

4. Passively Transferred Anti-Infectious Agents of Milk

   1. Front Matter

      Pages 199-199

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   2. Colostrum and Milk in the Treatment of Disease

      • Saeed Hosseini, Paula Inserra, Mohsen Araghi-Niknam, Ronald R. Watson

      Pages 201-212

   3. The Role of Human Milk Secretory IgA in Protecting Infants from Bacterial Enteritis

      • Marita Noguera-Obenza, Thomas G. Cleary

      Pages 213-229

   4. Chemistry of Milk Mucins and Their Anti-Microbial Action

      • H. Schroten

      Pages 231-245

   5. Antimicrobial Actions of Lactoferrin

      • Roberta Chierici

      Pages 247-269

   6. The Antimicrobial Function of Milk Lipids

      • Charles E. Isaacs

      Pages 271-285

   7. The Antimicrobial and Immunomodulating Actions of Milk Leukocytes

      • Gerd Riedel-Caspari

      Pages 287-307

5. Activity of Milk in Promoting Development of Immunocompetence in the Suckling Neonate

   1. Front Matter

      Pages 309-309

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   2. Maturation of Immunocompetence in Breast-Fed vs. Formula-Fed Infants

      • U. I. Dahlgren, L. Å. Hanson, E. Telemo

      Pages 311-325

This volume of Advances in Nutritional Research focuses on colostrum and milk as agents of defense against infection both for the suckling offspring and for the lactating mammary gland. The scope of the volume includes positive and negative influences of the consumption of mother's milk on the risk of infec­ tion, immunobiological roles of individual milk components, activities of milk and its components in promoting development of neonatal immunocompetence, the potential of milk and its components as therapeutic agents and as functional foods that support immune competence, and external influences that determine the immunological activity of milk. The volume is intended to provide a critical assessment of the limits of available information pertaining to humans and animals, together with authoritative comment regarding newer directions and unproven ideas. Part I provides a foundation for the volume. Readers unfamiliar with immunology will find, in Chapter 1, a selective outline of the anatomy and ontogeny of the mammalian immune system and of the types and regulation of immune defenses in mammals. Some emphasis is given to the place of the mammary gland within the common mucosal defense system, and to important species peculiarities in this regard. Chapter 2 is an authoritative and forward­ looking perspective on the development of knowledge pertaining to the immuno­ biology of milk as a fluid with both anti-infectious and anti-inflammatory roles. The chapter poses the provocative possibility of a tolerogenic role for milk.

• Allergie
• allergy
• chemistry
• nutrition
• processing

• University of Guelph, Guelph, Canada

  Bill Woodward, Harold H. Draper

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