Nutrition and Immunology

1. Front Matter

   Pages i-xiv

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2. Nutritional Assessment

   1. Front Matter

      Pages 1-1

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   2. Application and Interpretation of Commonly Used Nutritional Assessment Techniques

      • Kenneth H. Brown

      Pages 3-13

   3. Evaluating Malnutrition

      • Charles H. Halsted

      Pages 15-20

   4. Evaluation of the Immune System in the Nutritionally At-Risk Host

      • Jonathan Powell, Andrea T. Borchers, Steven Yoshida, M. Eric Gershwin

      Pages 21-31

3. Specific Nutrient Requirements

   1. Front Matter

      Pages 33-33

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   2. Caloric Intake: Sources, Deficiencies, and Excess—An Overview

      • Dean A. Troyer, Gabriel Fernandes

      Pages 35-47

   3. Protein and Amino Acids

      • Vernon R. Young

      Pages 49-64

   4. Specific Nutrient Requirements

      • Janet C. King

      Pages 65-74

   5. Vitamins

      • Robert Rucker

      Pages 75-96

   6. α-Lipoic Acid

      • John K. Lodge, Lester Packer

      Pages 97-106

   7. Defining the Role of Dietary Phytochemicals in Modulating Human Immune Function

      • Harold Schmitz, Kati Chevaux

      Pages 107-119

   8. Dietary n-3 Polyunsaturated Fatty Acids Modulate T-Lymphocyte Activation

      • Robert S. Chapkin, David N. McMurray, Christopher A. Jolly

      Pages 121-134

   9. Nucleotides

      • George K. Grimble, Olwyn M. R. Westwood

      Pages 135-144

4. Nutrient-Immune Interaction

   1. Front Matter

      Pages 145-145

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   2. Impact of Nutritional Status on Immune Integrity

      • Pam Fraker

      Pages 147-156

   3. Nutritional Modulation of Inflammation by Polyunsaturated Fatty Acids/Eicosanoids

      • Vincent A. Ziboh

      Pages 157-167

5. Clinical Issues

   1. Front Matter

      Pages 169-169

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   2. Immunological Considerations of Breast Milk

      • Bo Lönnerdal

      Pages 171-179

   3. Clinical Issues

      • Noel W. Solomons, Gerald T. Keusch

      Pages 181-194

It is a pleasure to write the foreword to Nutrition and Table 1 Nutritional Status and Outcome of Infection Immunology: Principles and Practice. In fact, this book comes at a timely moment, when the impact of nutrition and Definite adverse outcome immunology is being widely felt because of the AIDS epi­ Measles, diarrhea, tuberculosis demic. This is particularly of note in Africa, where large Probable adverse outcome HIV, malaria, pneumonia sums of money are being spent on nutritional intervention Little or no effect programs in the hopes of improving immune responsive­ Poliomyelitis, tetanus, viral encephalitis ness. We should not forget, however, early advances in our Note: HIV= human immunodeficiency virus understanding of protein energy malnutrition (PEM). PEM can be used as a model to understand the nutritional basis of immunity, as well as the immunological influences on nutri­ tional status. Despite advances in agricultural production, tance. However, both in vitro studies and tests in laboratory PEM continues to affect hundreds of millions ofthe world's animals may have little resemblance to what is experienced population. The functional impact of undernutrition varies in humans under field conditions. from mild morbidity to life-threatening infection.

• AIDS
• Amino acid
• Diabetes
• Lipid
• Malnutrition
• Nucleotide
• Nutrition
• allergy
• autoimmune disease
• breast feeding
• cancer
• infectious disease
• tea
• transcription

". . .this book comes at a timely moment, when the impact of nutrition and immunology is being widely felt because of the AIDS epidemic. . .There are a number of novel areas treated in this book that illustrate the changing tide and the great need to understand the molecular basis of interactions, in addition to understanding and performing simple dietary assessment."-Foreword by Ranjit Kumar Chandra, DSc, PhD, MD

"A wide range of topics are covered, beginning with chapters on nutritional assessment and nutrient requirements for a properly functioning immune system. The editors conclude with a series of discussions on nutrition and its role in a wide variety of clinical issues, ranging from a chapter on breast milk to the role of diet in various diseases. Chapters on alternative medicines and their effect on immunity are also included. This is a wealth of information that nutritionists, immunologists, and physicians may not always think about. Because of the many topics that are discussed, a large amount of information is provided in an accessible format with good references. . . Issues that are generally not included in immunology courses are compiled here, and probably should be. Most of the chapters are easy to read and contain some thought provoking material for discussion. This book could easily form the basis for a graduate level course.."-4 Stars!, Doody's Health Sciences Book Review Journal

"This unique book, authored by leading investigators in the field of nutrition and immune function, is a comprehensive, readable collection for both researchers and clinicians...Ten basic science chapters review the stat-of-the-art with regard to specific nutrients and their impact on immunity...All of the basic science chapters have outstanding figures of metabolic pathways, and nicely summarize the current understanding of cellular mechanisms. The chapters that examine specific clinical issues include several noteworthy contributions, particularly the chapters on nutrition and common oral diseases, and several superb reviews of nutritional therapy approaches to inflammatory and autoimmune diseases. There are also excellent chapters on AIDS, cancer, diabetes, allograft rejection, food toxicology, nutrition/immunity interactions, perioperative feeding, immune consequences of breast feeding, and a review of antioxidants in the aging immune system...this well-written, authoritative, and comprehensive book is a welcome addition and valuable reference for clinicians and investigators interested in modifying immune responses through nutrition." -Quarterly Review of Biology

"This is a substantial and well produced book in both physical and figurative senses, packed with information and references...provides a comprehensive review of the role of nutrition in health, with a major focus on how diet can reduce the onset and progression of numerous chronic diseases."-Nutrition and Health

"...this text is outstanding. If focuses attention on science issues and provides clear, understandable summaries of the state of current knowledge ...The chapter on nutrition and immunity in aging is an excellent example of the comprehensive and authoritative coverage of the topics listed." - Food and Nutrition Bulletin

"Of the recent books designed for this purpose, this text is outstanding. It focuses attention on science issues and provides clear, understandable summaries of the state of current knowledge....The chapter on nutrition and immunity in aging is an excellent example of the comprehensive and authoritative coverage of the topics listed." - Food and Nutrition Bulletin

"With contributions by 67 authors the editors of "Nutrition and Immunology" try to classify and evaluate the enormous and complex flood of data as one the well-known relationship between nutrition and state of immunity.... Against the background of growing "food-design" the relationships between nutritional and immunological research reach a completely new dimension. In the opinion of the authors this will require the establishment of a new field of nutritional science: nutritional immunology, which will be based on interdisciplinary research....The strong point of the book is the convincing extensive discussion of mainly clinical findings on the relationship between nutrition and immunity." - Nahrung/Food

• Division of Rheumatology/Allergy and Clinical Immunology, Department of Internal Medicine, University of California at Davis, Davis, USA

  M. Eric Gershwin

• Department of Food Science and Technology, University of California at Davis, Davis, USA

  J. Bruce German

• Department of Nutrition, University of California at Davis, Davis, USA

  Carl L. Keen

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