Regulation for Chemical Safety in Europe: Analysis, Comment and Criticism

1. Front Matter

   Pages i-x

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2. Introduction

   • D. M. Pugh, J. V. Tarazona

   Pages 1-3

3. Deciding on the Regulatory Limits Which Have Ensured that Exposures of People to Chemicals were without Unacceptable Risk

   • D. Michael Pugh

   Pages 7-26

4. Evaluation of Neurotoxicity

   • Eugenio Vilanova

   Pages 27-40

5. Scientific Concepts and Uncertainties in the Identification of Ecotoxicological Thresholds of Acceptability and Danger

   • J. V. Tarazona

   Pages 41-63

6. Simulation and Visualisation of Spatial Exposure Patterns

   • Frank Koormann, Michael Matthies, Stefan Trapp

   Pages 65-96

7. The Precautionary Principle and Science-Based Limits in Regulatory Toxicology

   • Finn Bro-Rasmussen

   Pages 97-111

8. Hazard Assessment and Risk Assessment of Chemical Substances in the EU

   • J. W. Hart, B. G. Hansen, W. Karcher

   Pages 113-125

9. Sustainable Development, Agricultural Practices and the Use of Plant Protection Products

   • Monika Herrchen, Werner Klein

   Pages 127-138

10. Options for the Regulation of the Long-Term Environmental Impact of Chemicals in the European Union

    • Robin Mason

    Pages 139-156

11. Regulations and Risk Assessments of the Ecotoxicological Impact from the Use of Plant Protection Products in the European Union

    • Nazim Punja

    Pages 157-169

12. Concluding Synthesis

    • D. Michael Pugh, Jose V. Tarazona

    Pages 171-180

13. Back Matter

    Pages 181-200

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Many European Union Directives seek to minimize the potential for harm to humans and the environment arising from the use of chemicals. This book takes an interdisciplinary, selective look at the effector mechanisms employed in such directives. It covers the pre-marketing use of toxicology to identify the hazardous properties of chemicals, acknowledging its shortcomings, while contrasting the scientific method with the precautionary principle in developing risk-management practices. The book then goes on to describe the use of bio-indicators, chemical analyses and mathematical modelling for prediction, or to determine the adequacy of chemical safety legislation. The environmental risk assessment of priority chemicals is described and the impact of pesticides on sustainability in agriculture is discussed from the differing standpoints of agronomy and economics.
Audience: All professionals concerned with the safe management of chemicals and their use, including teachers, practitioners, policy makers or legislators.

• Marketing
• development
• environment
• environmental risk assessment
• hazard
• neurotoxicity
• pesticide
• safety
• toxicity
• toxicology
• ecotoxicology

• Faculdade de Medicina Veterinaria, Universidade Tecnica de Lisboa, Portugal

  D. Michael Pugh

• Instituto Nacional de Investigacion y Tecnologia, Agraria y Alimentaria (INIA), Madrid, Spain

  Jose V. Tarazona

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