Biosensors for Environmental Diagnostics

1. Front Matter

   Pages 1-9

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2. New Techniques and Analytes

   1. Resonant Energy Transfer Detection for Low Volume Immunoassay in Environmental Applications

      • Andreas Brecht, Uwe Schobel, Günter Gauglitz

      Pages 11-27

   2. Screen-Printed Sensors and Biosensors for Environmental Applications

      • M. Del Carlo, A. Cagnini, I. Palchetti, S. Hernandez, M. Mascini

      Pages 28-44

   3. A Manufacturing Technology for Biosensing

      • Johanna C. Morey

      Pages 45-51

   4. Development of an Enzyme-Linked Immunosorbent Assay for the Determination of Irgarol 1051

      • M.-P. Marco, B. Ballesteros, I. Ferrer, J. Casas, D. Barceló

      Pages 52-63

   5. Immunosensor Systems with Renewable Sensing Surfaces

      • M. Santandreu, S. Solé, S. Alegret, E. Martínez-Fàbregas

      Pages 64-89

3. Industrial Pollutants

   1. Catalytic and Affinity Amperometric Biosensors for Phenols, Phosphates, and Atrazine: How Transduction Can Improve Performance

      • Arántzazu Narváez, Miguel Angel López, Elena González, Elena Domínguez, Juan José Fernández, Ioanis Katakis

      Pages 90-107

   2. A Master Analytical Protocol for Determining a Broad Spectrum of Organic Pollutants in Industrial Effluents

      • M. Castillo, A. Oubiña, J. S. Salau, J. Gascón, D. Barceló

      Pages 108-128

4. Pesticides

   1. Measurement of Priority Metabolites Using Integrated Optoelectronic Biosensors Derived from Antibody and Synthetic Receptor Libraries

      • Anthony P. F. Turner, Andrew Rickman, Bertold Hock, Rolf D. Schmid, Damia Barceló

      Pages 129-146

   2. River Analyser — Multiresidue Immunoanalytical Monitoring Tools

      • Andreas Brecht, Claudia Barzen, Albrecht Klotz, Günter Gauglitz, Richard Harris, Geoffrey Quigley et al.

      Pages 147-160

   3. Strategies for Recombinant Antibody Library Synthesis: An Advanced Source for Immunoglobulins in Environmental Analysis

      • Karl Kramer, Achim Knappik

      Pages 161-178

   4. Characterization of a Monoclonal Antibody and its Fab Fragment Against Diphenylurea Hapten with BIA

      • Walter F. M. Stöcklein, Axel Warsinke, Burkhard Micheel, Wolfgang Höhne, Gerhard Kempter, Frieder W. Scheller

      Pages 179-194

5. Monitoring of Toxic Effects

   1. Endocrine Disruptors: Monitoring of Effects

      • Bertold Hock, Martin Seifert

      Pages 195-214

6. Monitoring of Genotoxicity

   1. Recombinant Escherichia Coli Cells as Biodetector System for Genotoxins

      • Gerda Horneck, Leonid R. Ptitsyn, Petra Rettberg, Olga Komova, Stanislav Kozubek, Eugene A. Krasavin

      Pages 215-232

7. Field Experiments

   1. Potential and Capabilities of Biosensors for the Assessment of Environmental Pollutants

      • Karl Cammann, Gabriele Chemnitius, Markus Meusel, Christiane Zaborosch

      Pages 233-252

   2. Vitellogenin — A Biomarker for Endocrine Disruptors

      • P.-D. Hansen, H. Dizer, B. Hock, A. Marx, J. Sherry, M. McMaster et al.

      Pages 253-261

8. Perspectives

   1. How Could a Concerted Action Guide Technological Developments in the Field of Biosensors?

      • S. J. Alcock, A. P. F. Turner

      Pages 262-271

9. Back Matter

   Pages 272-280

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Biosensors combine the power of microelectronics with the selectivity and sensitivity of biological components such as whole cells, organelles or biomolecules, e.g. antibodies, receptors, enzymes and nucleic acids. They are used to detect individual substances or groups of substances in the environment, such as industrial emissions that originate, for instance, from the textile, cellulose and pharmceutical industry as well as from agricultural activities. The biosensor approach is expected not only to provide a significant contribution to measurement technology but also a basis for competent political decisions. Up to now disturbances in lakes and rivers are detected more or less by chance. Essentially, only substances that can be assayed by traditional physico-chemical techniques are found. However, the pollution peak has usually already passed by the time the results become known and acquisition of evidence for the identification of the responsible party is hardly possible after the event. Therefore fast and continuous measurement systems such as biosensors are required to provide inexpensive and cost effective event-related sampling of water thus providing for the preservation of evidence. Biosensors can detect biological effects such as genotoxicity, immunotoxicity and endocrine responses. The sequence of these signals and especially the peak values provide valuable indicators for water protection and facilitate the elaboration of new strategies and concepts within water management. Of major importance is the knowledge of distribution of warning signals within space and time from water ecosystems. Only then can the "health status" of water be recognized sufficiently early.

• Sensor
• biosensor
• development
• energy
• environment
• environmental monitoring
• enzymes
• measurement technology
• microelectronics
• microorganism
• technology
• transducer

• Technische Universität München, Germany

  Bertold Hock

• Department of Environmental Chemistry Barcelona, Spain

  Damià Barceló

• Institut für Chemo- und Biosensorik Münster, Germany

  Karl Cammann

• Technische Universität Berlin, Germany

  Peter-Diedrich Hansen

• Cranfield University, UK

  Anthony P. F. Turner

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