The paper selected for the 2007 Nightingale Prize is entitled ‘An effective non-parametric method for globally clustering genes from expression profiles’ by Hou et al. The authors are from two different institutions in Australia: the School of Engineering and Information Technology, Deakin University Burwood and The Walter and Eliza Hall Institute of Medical Research, Parkville. According to an expert reviewer: ‘The key strength is the interesting novel algorithm for studying clustering genes and the paper outlines in welcome detail the mathematical underpinnings of this approach. The method was validated on both synthetic and real datasets’. We wholeheartedly congratulate the authors on their outstanding achievement.