The Journal of Clinical Immunology publishes papers in the area of Human Immunology. Human Immunology includes research utilizing human subjects or human materials as well as studies of animal models of human diseases. The Journal is particularly interested in the areas of primary immune deficiency, immunodysregulation, immunologic interventions, and diagnostic approaches to immunologically mediated diseases, including biomarkers. Case reports will only be considered if they are linked to novel new findings/science or are accompanied by succinct review of the relevant medical literature to the novel findings identified in the case report. Topical reviews are by invitation only.