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  • © 2016

The Microtubule Cytoskeleton

Organisation, Function and Role in Disease

Editors:

  • Most comprehensive work on the biology and function of microtubules on the market

  • Treats basic mechanisms and organization of the microtubule cytoskeleton as well its involvement in disease

  • Describes function, maintenance and biogenesis of microtubules based organelles

  • Includes supplementary material: sn.pub/extras

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-vii
  2. Microtubule Organization in Mitotic Cells

    • Sylvain Meunier, Isabelle Vernos
    Pages 1-26
  3. Non-centrosomal Microtubule Organization in Differentiated Cells

    • Vyacheslav Dyachuk, Christiane Bierkamp, Andreas Merdes
    Pages 27-41
  4. Organizational Properties of the Pericentriolar Material

    • David Comartin, Laurence Pelletier
    Pages 43-77
  5. Principles of Microtubule Organization: Insight from the Study of Neurons

    • Carlos Sánchez-Huertas, Francisco Freixo, Jens Lüders
    Pages 79-115
  6. Consequences of Numerical Centrosome Defects in Development and Disease

    • Davide Gambarotto, Renata Basto
    Pages 117-149
  7. Microtubules Regulate Cell Migration and Neuronal Pathfinding

    • Ulrike Theisen, Anne Straube
    Pages 151-189

About this book

This book provides an overview on the organization and function of the microtubule cytoskeleton, which is essential to many cellular processes and profoundly linked to a range of human diseases. Covering basic concepts as well as molecular details, the book discusses how microtubules are nucleated and organized into ordered arrays, at different cell cycle stages and in distinct cell types. In addition, the book highlights how defects in the microtubule cytoskeleton are linked to diseases such as neurodevelopmental disorders.

The book is intended for students, graduates and more senior researchers in cell and developmental biology as well as for medical doctors.

Editors and Affiliations

  • The Barcelona Institute of Science and T, Institute for Research in Biomedicine (I, Barcelona, Spain

    Jens Lüders

About the editor

Jens Lüders, PhD, is leading the Microtubule organization group at the Institute for Research in Biomedicine (IRB), in Barcelona, Spain. 


Bibliographic Information

  • Book Title: The Microtubule Cytoskeleton

  • Book Subtitle: Organisation, Function and Role in Disease

  • Editors: Jens Lüders

  • DOI: https://doi.org/10.1007/978-3-7091-1903-7

  • Publisher: Springer Vienna

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Wien 2016

  • Softcover ISBN: 978-3-7091-1901-3Published: 19 April 2016

  • eBook ISBN: 978-3-7091-1903-7Published: 08 April 2016

  • Edition Number: 1

  • Number of Pages: VII, 189

  • Number of Illustrations: 6 b/w illustrations, 14 illustrations in colour

  • Topics: Cell Physiology, Molecular Medicine, Developmental Biology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access