Overview
- Updated and expanded new edition
- New, practical exercises suitable both for courses and self-teaching
- Written by an experienced lecturer and researcher
- Case studies, exercises with solutions and worked-out examples are included to demonstrate and practice
- Not only beginners, but also more experienced bioinformaticists will be able to gather new insights
- Shows how to efficiently extract, organize and visualize information from large datasets
- Includes supplementary material: sn.pub/extras
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Table of contents (21 chapters)
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Front Matter
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Whetting Your Appetite
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Front Matter
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Computer & Operating Systems
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Front Matter
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Programming
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Front Matter
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Keywords
About this book
This greatly expanded 2nd edition provides a practical introduction to
- data processing with Linux tools and the programming languages AWK and Perl
- data management with the relational database system MySQL, and
- data analysis and visualization with the statistical computing environment R
for students and practitioners in the life sciences. Although written for beginners, experienced researchers in areas involving bioinformatics and computational biology may benefit from numerous tips and tricks that help to process, filter and format large datasets. Learning by doing is the basic concept of this book. Worked examples illustrate how to employ data processing and analysis techniques, e.g. for
- finding proteins potentially causing pathogenicity in bacteria,
- supporting the significance of BLAST with homology modeling, or
- detecting candidate proteins that may be redox-regulated, on the basis of their structure.
All the softwaretools and datasets used are freely available. One section is devoted to explaining setup and maintenance of Linux as an operating system independent virtual machine. The author's experiences and knowledge gained from working and teaching in both academia and industry constitute the foundation for this practical approach.
Authors and Affiliations
About the author
Bibliographic Information
Book Title: Computational Biology
Book Subtitle: A Practical Introduction to BioData Processing and Analysis with Linux, MySQL, and R
Authors: Röbbe Wünschiers
DOI: https://doi.org/10.1007/978-3-642-34749-8
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2013
Hardcover ISBN: 978-3-642-34748-1Published: 31 January 2013
Softcover ISBN: 978-3-642-43097-8Published: 26 June 2015
eBook ISBN: 978-3-642-34749-8Published: 30 January 2013
Edition Number: 2
Number of Pages: XXIX, 449
Number of Illustrations: 12 b/w illustrations, 66 illustrations in colour
Topics: Computer Appl. in Life Sciences, Bioinformatics, Proteomics, Biochemistry, general, Computer Applications, Biological and Medical Physics, Biophysics