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Computer Science - Theoretical Computer Science | Discrete and Topological Models in Molecular Biology

Discrete and Topological Models in Molecular Biology

Jonoska, Nataša, Saito, Masahico (Eds.)

2014, XIII, 524 p. 211 illus., 154 illus. in color.

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  • Methods allow researchers to "zoom in" on processes at a molecular level
  • Contributing authors are among the leading scientists in this field
  • Reference for researchers in mathematics, theoretical computer science, mathematical biology and bioinformatics

Theoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molec­ular level.

 This book contains expository chapters on how contemporary models from discrete mathematics – in do­mains such as algebra, combinatorics, and graph and knot theories – can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions.

 The contributing authors are among the leading scientists in this field and the book is a reference for re­searchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology.

Content Level » Research

Keywords » Cell biology - DNA - Evolutionary biology - Gene assembly - Genome analysis - Genome processing - RNA - Recombination - Self-assembly - Systems biology

Related subjects » Biophysics & Biological Physics - Cell Biology - Evolutionary & Developmental Biology - Theoretical Computer Science

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