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Approaches in Integrative Bioinformatics

Towards the Virtual Cell

  • Book
  • © 2014

Overview

Editors:
  1. Ming Chen

    1. College of Life Sciences, Zhejiang University, Hangzhou, People's Republic of China

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    You can also search for this editor in PubMed   Google Scholar

  2. Ralf Hofestädt

    1. Department of Bioinformatics and Medical Informatics, Bielefeld University, Bielefeld, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Presents a summary of essential topics, basic introductions and latest developments in integrative bioinformatics
  • Introduces a key point to understand the mechanism of life, i.e. the systems biology towards the virtual cell study
  • Contributed by many distinguished experts worldwide

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. Integrative Bioinformatics

      • Ming Chen, Ralf Hofestädt
      Pages 3-19

    3. An Overview of Gene Regulation

      • Andrew Harrison, Hugh Shanahan
      Pages 21-69

  3. Information Fusion and Retrieval

    1. Front Matter

      Pages 71-71
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    2. Information Retrieval in Life Sciences: A Programmatic Survey

      • Matthias Lange, Ron Henkel, Wolfgang Müller, Dagmar Waltemath, Stephan Weise
      Pages 73-109

    3. Data Warehouses in Bioinformatics

      • Benjamin Kormeier
      Pages 111-130

    4. Molecular Information Fusion in Ondex

      • Jan Taubert, Jacob Köhler
      Pages 131-160

    5. Text Mining on PubMed

      • Timofey V. Ivanisenko, Pavel S. Demenkov, Vladimir A. Ivanisenko
      Pages 161-170

  4. Network Visualization, Modeling and Analysis

    1. Front Matter

      Pages 171-171
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    2. Network Visualization for Integrative Bioinformatics

      • Andreas Kerren, Falk Schreiber
      Pages 173-202

    3. Biological Network Modeling and Analysis

      • Sebastian Jan Janowski, Barbara Kaltschmidt, Christian Kaltschmidt
      Pages 203-244

    4. Petri Nets for Modeling and Analyzing Biochemical Reaction Networks

      • Fei Liu, Monika Heiner
      Pages 245-272

  5. BioData Mapping

    1. Front Matter

      Pages 273-273
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    2. Network Analysis and Integration in a Virtual Cell Environment

      • Björn Sommer
      Pages 275-297

    3. Bridging Genomics and Phenomics

      • Dijun Chen, Ming Chen, Thomas Altmann, Christian Klukas
      Pages 299-333

  6. Biocompution

    1. Front Matter

      Pages 335-335
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    2. Parallel Computing for Gene Networks Reverse Engineering

      • Jaroslaw Zola
      Pages 337-354

    3. Computational Biomarker Discovery

      • Fan Zhang, Xiaogang Wu, Jake Y. Chen
      Pages 355-386
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Keywords

About this book

Approaches in Integrative Bioinformatics provides a basic introduction to biological information systems, as well as guidance for the computational analysis of systems biology. This book also covers a range of issues and methods that reveal the multitude of omics data integration types and the relevance that integrative bioinformatics has today. Topics include biological data integration and manipulation, modeling and simulation of metabolic networks, transcriptomics and phenomics, and virtual cell approaches, as well as a number of applications of network biology. It helps to illustrate the value of integrative bioinformatics approaches to the life sciences. This book is intended for researchers and graduate students in the field of Bioinformatics. Professor Ming Chen is the Director of the Bioinformatics Laboratory at the College of Life Sciences, Zhejiang University, Hangzhou, China. Professor Ralf Hofestädt is the Chair of the Department of Bioinformatics and Medical Informatics, Bielefeld University, Germany.

Reviews

From the book reviews:

“This very well-edited and coherent book can be useful both to data scientists who would like to know how their discipline can be applied to a rich domain, and also to biologists who are getting more and more convinced of the need to access sophisticated software tools to take their research forward.” (Sara Kalvala, Computing Reviews, September, 2014)

Editors and Affiliations

  • College of Life Sciences, Zhejiang University, Hangzhou, People's Republic of China

    Ming Chen

  • Department of Bioinformatics and Medical Informatics, Bielefeld University, Bielefeld, Germany

    Ralf Hofestädt

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