Bioinformatics in Personalized Medicine

1. Front Matter

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2. Statistical Significance for NGS Reads Similarities

   • Antonio Muñoz-Mérida, Javier Ríos, Hicham Benzekri, Oswaldo Trelles

   Pages 1-7

3. Application of Array-Oriented Scientific Data Formats (NetCDF) to Genotype Data, GWASpi as an Example

   • Fernando Muñiz Fernandez, Angel Carreño Torres, Carlos Morcillo-Suarez, Arcadi Navarro

   Pages 8-20

4. An Ontology and a REST API for Sequence Based Microbial Typing Data

   • João Almeida, João Tiple, Mário Ramirez, José Melo-Cristino, Cátia Vaz, Alexandre P. Francisco et al.

   Pages 21-28

5. Multivariate Methods for the Integration and Visualization of Omics Data

   • Alex Sánchez, José Fernández-Real, Esteban Vegas, Francesc Carmona, Jacques Amar, Remy Burcelin et al.

   Pages 29-41

6. A Holistic Approach for Integrating Genomic Variation Information

   • Pedro Lopes, José Luís Oliveira

   Pages 42-49

7. SB-KOM: Integration of Pathway Information with BioPax

   • María Jesús García-Godoy, Ismael Navas-Delgado, José F. Aldana-Montes

   Pages 50-65

8. GENote v.β: A Web Tool Prototype for Annotation of Unfinished Sequences in Non-model Eukaryotes

   • Noé Fernández-Pozo, Darío Guerrero-Fernández, Rocío Bautista, Josefa Gómez-Maldonado, Concepción Avila, Francisco M. Cánovas et al.

   Pages 66-71

9. Interface Similarity Improves Comparison of DNA-Binding Proteins: The Homeobox Example

   • Álvaro Sebastián, Carlos P. Cantalapiedra, Bruno Contreras-Moreira

   Pages 72-82

10. Pyicos: A Flexible Tool Library for Analyzing Protein-Nucleotide Interactions with Mapped Reads from Deep Sequencing

    • Juan González-Vallinas, Sonja Althammer, Eduardo Eyras

    Pages 83-88

11. Novel Angiogenic Functional Targets Predicted through “Dark Matter” Assessment in Protein Networks

    • Ian Morilla, Miguel A. Medina, Juan A. G. Ranea

    Pages 89-93

12. jORCA and Magallanes Sailing Together towards Integration of Web Services

    • Johan Karlsson, Oswaldo Trelles

    Pages 94-101

13. iHOP Web Services Family

    • José M. Fernández, Robert Hoffmann, Alfonso Valencia

    Pages 102-107

14. Bioinformatic Software Developments in Spain

    • José M. Fernández, Alfonso Valencia

    Pages 108-120

15. Back Matter

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This book constitutes the refereed proceedings of the 10th Spanish Symposium on Bioinformatics, JBI 2010, held in Torremolinos, Spain, in October 2010. The 13 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers are structured in topical sections on next-generation sequencing data; genome-wide association studies; high-performanced databases; text-mining; tools for integration of Web services; ontologies; analysis and visualization of omics data.

• DNA motif
• Web services
• omic data
• software development
• text mining

• INESC-ID/Instituto Superior Técnico, Lisboa, Portugal

  Ana T. Freitas

• Institut de Biologia Evolutiva (UPF-CSIC), Barcelona, Spain

  Arcadi Navarro

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