Skip to main content
  • Book
  • © 2010

Transactions on Computational Systems Biology XII

Special Issue on Modeling Methodologies

  • Contains theoretical, applicational and technical papers on the broad area of computational systems biology.
  • This special issue focuses on the topic of modeling methodologies.
  • It includes a position paper by the guest editors.

Part of the book series: Lecture Notes in Computer Science (LNCS, volume 5945)

Part of the book sub series: Transactions on Computational Systems Biology (TCSB)

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (7 chapters)

  1. Front Matter

  2. Biomodel Engineering – From Structure to Behavior

    • Rainer Breitling, Robin A. Donaldson, David R. Gilbert, Monika Heiner
    Pages 1-12
  3. The Attributed Pi-Calculus with Priorities

    • Mathias John, Cédric Lhoussaine, Joachim Niehren, Adelinde M. Uhrmacher
    Pages 13-76
  4. A Language for Biochemical Systems: Design and Formal Specification

    • Michael Pedersen, Gordon D. Plotkin
    Pages 77-145
  5. Mechanistic Insights into Metabolic Disturbance during Type-2 Diabetes and Obesity Using Qualitative Networks

    • Antje Beyer, Peter Thomason, Xinzhong Li, James Scott, Jasmin Fisher
    Pages 146-162
  6. Modelling Self-assembly in BlenX

    • Roberto Larcher, Corrado Priami, Alessandro Romanel
    Pages 163-198
  7. Rule-Based Modeling of Transcriptional Attenuation at the Tryptophan Operon

    • Céline Kuttler, Cédric Lhoussaine, Mirabelle Nebut
    Pages 199-228
  8. Modelling and Analysis of the NF-κB Pathway in Bio-PEPA

    • Federica Ciocchetta, Andrea Degasperi, John K. Heath, Jane Hillston
    Pages 229-262
  9. Back Matter

About this book

The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena.

This special issue of the journal focuses on the topic of modeling methodologies. It starts with a position paper by the guest editors, entitled Biomodel Engineering - from Structure to Behavior, which is followed by the technical contributions covering a broad range of modeling methodologies. Two papers focus on new modeling languages, and these are followed by an article presenting a case study demonstrating the value of the qualitative network approach. With the remaining three contributions, the special issue leaves the area of qualitative modeling, to move toward quantitative programming with the BlenX language and the application of more theoretical process calculi.

Editors and Affiliations

  • Centre for Computational and Systems Biology, The Microsoft Research - University of Trento, Povo (TN), Italy

    Corrado Priami

  • Groningen Bioinformatics, University of Groningen, Haren, The Netherlands

    Rainer Breitling

  • School of Information Systems, Brunel University, Uxbridge, UK

    David Gilbert

  • Computer Science Institute, Brandenburg University of Technology, Cottbus, Germany

    Monika Heiner

  • Institute of Computer Science, University of Rostock, Rostock, Germany

    Adelinde M. Uhrmacher

Bibliographic Information

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access