The biological activity of mycotoxins ranges from weak and/or sometimes positive effects, such as antibacterial activity (see penicillin derivatives derived from Penicillium strains) to strong mutagenic (e. g. aflatoxins, patulin), carcinogenic (e. g. aflatoxins), teratogenic, neurotoxic (e. g. ochratoxins), nephrotoxic (e. g. fumonisins, citrinin), hepatotoxic, and immunotoxic (e. g. ochratoxins, diketopiperazines) activity. Nowadays, many laboratories around the world are specialized in the detection of mycotoxins in food products and contaminated material found in housing. In this volume, a focus on the most important classes of mycotoxins is provided and their chemistry of the last ten years is discussed. In each Section, the individual biological impact is outlined. Sections are arranged according to mycotoxin classes (e. g. aflatoxins) and/or structural classes (e. g. resorcinyl lactones, diketopiperazines). The biology of mycotoxins is also described.
Reviews
From the reviews:
“‘The chemistry of mycotoxins’ written by Bräse et al. gives detailed insight into the total synthesis of several classes of mycotoxins discussing various strategies and structural aspects. … the book provides a lot of information and should therefore definitely be recommended to natural product and/or synthetic chemists that are interested in this particular topic.” (H. Mikula, World Mycotoxin Journal, Vol. 6 (4), November, 2013)
Authors and Affiliations
Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany
Stefan Bräse,
Franziska Gläser,
Carsten Kramer,
Anna M. Linsenmeier,
Kye-Simeon Masters,
Anne C. Meister,
Bettina M. Ruff,
Sabilla Zhong
, Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany
Stephanie Lindner
Bibliographic Information
Book Title: The Chemistry of Mycotoxins
Authors: Stefan Bräse, Franziska Gläser, Carsten Kramer, Stephanie Lindner, Anna M. Linsenmeier, Kye-Simeon Masters, Anne C. Meister, Bettina M. Ruff, … Sabilla Zhong
