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Chemistry - Organic Chemistry | Fragment-Based Drug Discovery and X-Ray Crystallography

Fragment-Based Drug Discovery and X-Ray Crystallography

Series: Topics in Current Chemistry, Vol. 317

Davies, Thomas G., Hyvönen, Marko (Eds.)

2012, XII, 228 p.

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  • This series presents critical reviews of the present position and future trends in modern chemical research
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D. A. Erlanson Introduction to Fragment-Based Drug Discovery T. G. Davies Ian J. Tickle Fragment Screening Using X-Ray Crystallography S. Roughley L. Wright P. Brough A. Massey R. E. Hubbard Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening D. F. Wyss Y.-S. Wang H. L. Eaton C. Strickland J.s H. Voigt Z. Zhu A. W. Stamford Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors M. Hennig A. Ruf Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery E. Valkov T. Sharpe M. Marsh Sa. Greive M. Hyvönen Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery J.h D. Bauman D. Patel E. Arnold Fragment Screening and HIV Therapeutics D. Rognan Fragment-Based Approaches and Computer-Aided Drug Discovery

Content Level » Research

Keywords » Astex Pharmaceuticals - Biophysical Screening - Computer Aided Drug Discovery - Fragment Screening - Fragment-Based Drug Discovery - Hsp90 Inhibitors - Protein-Protein Interactions - Review - Selective BACE-1 Inhibitors - Virtual Screening

Related subjects » Materials - Organic Chemistry - Pharmacology & Toxicology

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