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Chemistry | Pharmacogenomics in Drug Discovery and Development

Pharmacogenomics in Drug Discovery and Development

Series: Methods in Molecular Biology, Vol. 448

Yan, Qing (Ed.)

2008, XIII, 487 p.

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  • Examines both fundamental concepts and advanced technologies in pharmacogenomics
  • Uses cutting-edge technologies to pursue systems-based pharmacogenomics, including bioinformatics, microarray, and association studies
  • Methodical, state-of-the-art contributions cover topics from individual molecules and gene-drug interactions to systemic diseases
  • Explores extensive applications of pharmacogenomics in drug development for diseases, including psychiatric disorders, cardiovascular diseases, cancer, Alzheimer's disease, rheumatoid arthritis, asthma, and infectious diseases

Since each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body.  In Pharmacogenomics in Drug Discovery and Development, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies.  Divided into three sections, the volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. Although not in standard Methods in Molecular Biology™ series format, the book retains the practicality and usefulness of the highly successful series.

Comprehensive and up-to-date, Pharmacogenomics in Drug Discovery and Development is an ideal volume for scientists striving to transform disease treatment into disease prevention.

Content Level » Research

Keywords » Asthma - Biomarker genes and pathways - Biomarkers - Drug response phenotypes - Gene-drug interactions - Genotypes - Personalized medicine - Therapeutics of disease - dopamine

Related subjects » Cell Biology - Chemistry - Human Genetics - Pharmacology & Toxicology - Systems Biology and Bioinformatics

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Distribution rights for India: CBS Publishers, New Delhi, India

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