Logo - springer
Slogan - springer

Chemistry - Biotechnology | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes

Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes

Series: Springer Theses

Daumann, Lena

2014, XXI, 239 p. 200 illus., 22 illus. in color.

Available Formats:
eBook
Information

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.

 
$99.00

(net) price for USA

ISBN 978-3-319-06629-5

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase


learn more about Springer eBooks

add to marked items

Hardcover
Information

Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$129.00

(net) price for USA

ISBN 978-3-319-06628-8

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

  • Nominated as an Outstanding Ph.D. thesis by the University of Queensland, Australia
  • Encompasses a broad range of topics including biochemical, kinetic and mechanistic studies, chemical synthesis, as well as the use of polymeric and nanoparticle supports
  • Enhances our understanding of hydrolytic cleavage of important substrates like phosphoesters and β-lactams
  • Includes a short introduction to each chapter to guide non-specialist readers
Lena Daumanns's thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mimics of this enzyme and related binuclear metallohydrolases such as the metallo-ß-lactamases to enhance our understanding of hydrolytic cleavage of important substrates like phosphoesters and β-lactams. Overall, this project has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides. Analysis shows that both the enzyme and biomimetics can be stored on the solid support without loss of activity. Furthermore, the author specroscopically and mechanistically characterized a number of Zn(II), Cd(II) and Co(II) complexes, some of which are among the most active biomimetics towards organophosphates reported to date. This thesis makes excellent reading for non-specialists because each chapter includes a short introduction section.

Content Level » Research

Keywords » Antibiotic Resistance - Bioinspired Hydrolysis - Biomimetic Complex - Dinuclear Cobalt Complexes Magnetism - Magnetic Circular Dichrosim - Metallo-beta-lactamase - Organophosphate Pesticide Bioremediation - Phosphoesterase Enzymes

Related subjects » Analytical Chemistry - Biotechnology

Table of contents / Sample pages 

Popular Content within this publication 

 

Articles

Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Biochemical Engineering.