Logo - springer
Slogan - springer

Chemistry - Analytical Chemistry | Studying Cell Metabolism and Cell Interactions Using Microfluidic Devices Coupled with Mass Spectrometry

Studying Cell Metabolism and Cell Interactions Using Microfluidic Devices Coupled with Mass Spectrometry

Series: Springer Theses

Wei, Huibin

2013, XVI, 104 p.

Available Formats:
eBook
Information

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.

 
$99.00

(net) price for USA

ISBN 978-3-642-32359-1

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase


learn more about Springer eBooks

add to marked items

Hardcover
Information

Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$129.00

(net) price for USA

ISBN 978-3-642-32358-4

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

Softcover
Information

Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$129.00

(net) price for USA

ISBN 978-3-642-43086-2

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

  • Describes a new cell analysis platform which combines microfluidic device with mass spectrometry to determine trace chemicals secreted by the cells
  • Develops microfluidic devices integrating the functions of cell culture, drug stimulation, and secretion pretreatment
  • Invents an energy-saving cell sorting microluidic device, which successfully achieved a separation efficiency of 97%
  • Establishes a cell co-culture microfluidic device to study the signal transmission functions between related organisms
  • Nominated as an outstanding contribution by Department of Chemistry, Tsinghua University

This thesis describes a new approach for cell analysis by the rapid developing microfluidic technology. The nominee has made great contributions to develop a new analysis platform which combined microfluidic devices with mass spectrometry to determine the trace compounds secreted by cells. Based on this analysis platform, she studied the specific cell secreting behaviors under controlled microenvironment, of which the secretion compounds were qualified and semi-quantified by mass spectrometry. A novel cell sorting device integrated homogenous porous PDMS membrane was invented to classify cells from real samples based on the size difference. The nominee further studied the signal transmission between different cells, and the signal chemicals were qualitative and quantitative monitored by the analysis platform. This indicates the potential significant application of the new cell analysis platform in medicine screening and early diagnosis.

Content Level » Research

Keywords » Cell Secretion - Electrospray Lonization - Mass Spectrometry - Microfluidics Devices - Signal Transmission - Signaling Factor

Related subjects » Analytical Chemistry - Cell Biology - Engineering

Table of contents 

Introduction.- Analysis of Herbicides on a Single C30 Bead via the Platform Combined Microfluidic Device with ESI-Q-TOF-MS.- Monitoring of Glutamate Release from Neuronal Cell Based on the Analysis Platform Combining the Microfluidic Devices with ESI-Q-TOF-MS.- Microfluidic Device with Integrated Porous Membrane for Cell Sorting and Separation.- Cell Co-culture and Signaling Analysis Based on Microfluidic Devices Coupling with ESI-Q-TOF-MS.

Popular Content within this publication 

 

Articles

Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Mass Spectrometry.