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  • Book
  • © 2008

Natural Compounds as Drugs, Volume II

Birkhäuser
  • Highlights innovative opportunities in drug discovery
  • Overview of strategies and screening methods
  • Compilation of current applicable technology
  • Includes supplementary material: sn.pub/extras

Part of the book series: Progress in Drug Research (PDR, volume 66)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-x
  2. Activation of fungal silent gene clusters: A new avenue to drug discovery

    • Axel A. Brakhage, Julia Schuemann, Sebastian Bergmann, Kirstin Scherlach, Volker Schroeckh, Christian Hertweck
    Pages 1-12
  3. Chemical-genetic approaches for exploring the mode of action of natural products

    • Andres Lopez, Ainslie B. Parsons, Corey Nislow, Guri Giaever, Charles Boone
    Pages 237-271
  4. Histone deacetylase inhibitors from microorganisms: the Astellas experience

    • Yuhta Masuoka, Nobuaki Shindoh, Noriaki Inamura
    Pages 335-359
  5. Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720

    • Peter C. Hiestand, Martin Rausch, Daniela Piani Meier, Carolyn A. Foster
    Pages 361-381
  6. Back Matter

    Pages 423-427

About this book

The use of substances derived from plants, fungi, bacteria and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today's pharmaceutical market.

In molecular biological research, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors.

This book highlights the biodiversity-driven approaches which are now of eminent importance in natural products research. It addresses the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.

Reviews

From the reviews:

“This second compilation highlights innovative trends in natural products research. … provide very diverging aspects from molecular biology to practical questions such as production optimization strategies. … This well-designed volume provides reviews of constant quality in the important field of modern drug research written by an international crew of experts. … Figures / schemes (numerous formulas) and tables are useful and well organized. … I recommend this book to anyone interested in modern drug research. It would best be suited for science and industry libraries.” (Eckart Eich, Economic Botany, Vol. 63 (4), 2009)

Editors and Affiliations

  • Novartis Pharma AG, Basel, Switzerland

    Frank Petersen, René Amstutz

Bibliographic Information

  • Book Title: Natural Compounds as Drugs, Volume II

  • Editors: Frank Petersen, René Amstutz

  • Series Title: Progress in Drug Research

  • DOI: https://doi.org/10.1007/978-3-7643-8595-8

  • Publisher: Birkhäuser Basel

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Birkhäuser Basel 2008

  • Hardcover ISBN: 978-3-7643-8594-1Published: 13 March 2008

  • eBook ISBN: 978-3-7643-8595-8Published: 29 July 2008

  • Series ISSN: 0071-786X

  • Series E-ISSN: 2297-4555

  • Edition Number: 1

  • Number of Pages: X, 428

  • Number of Illustrations: 185 b/w illustrations, 27 illustrations in colour

  • Topics: Pharmacology/Toxicology, Biochemistry, general

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access