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Birkhäuser

Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis and Pharmacotherapy

  • Book
  • © 2009

Overview

Editors:
  1. Carlos A. Zarate

    1. Mood Disorders Research Unit Laboratory of Molecular Pathophysiology, National Institute of Mental Health Mark O. Hatfield Clinical Research Center, Bethesda, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Husseini K. Manji

    1. Laboratory of Molecular Pathophysiology, National Institute of Mental Health Porter Neuroscience Research Center, Bethesda, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive volume covering neurobiology, clinical results and the development of novel therapeutics
  • Edited by leading experts in the field
  • International authorship
  • Includes supplementary material: sn.pub/extras

Part of the book series: Milestones in Drug Therapy (MDT)

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Table of contents (16 chapters)

  1. Front Matter

    Pages I-XII
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  2. Bipolar depression: Clinical phenotype and course of illness

    1. Front Matter

      Pages 1-1
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    2. The history of bipolar disorders

      • Andreas Marneros
      Pages 3-16

    3. The clinical diagnosis of bipolar depression

      • Gordon B. Parker, Kathryn Fletcher
      Pages 17-28

    4. Course and outcome of bipolar disorder — focusing on depressive aspects

      • Tamas Treuer, Mauricio Tohen
      Pages 29-46

    5. Suicide and bipolar disorder

      • Zoltán Rihmer
      Pages 47-56

  3. Bipolar depression: Neurobiology

    1. Front Matter

      Pages 57-57
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    2. The genetic basis of bipolar disorder

      • Thomas G. Schulze, Francis J. McMahon
      Pages 59-76

    3. Understanding the neurobiology of bipolar depression

      • Jun-Feng Wang, L. Trevor Young
      Pages 77-94

    4. Non-pharmacological treatments and chronobiological aspects of bipolar disorder: implications for novel therapeutics

      • Wallace C. Duncan Jr
      Pages 95-116

    5. Neuroimaging studies of bipolar depression: therapeutic implications

      • Jonathan Savitz, Wayne C. Drevets
      Pages 117-144

  4. Acute and long-term treatment of bipolar disorder

    1. Front Matter

      Pages 145-145
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    2. Pharmacological treatment of acute bipolar depression

      • Gary S. Sachs, Louisa G. Sylvia, Hannah G. Lund
      Pages 147-158

    3. Pharmacological treatment of the maintenance phase of bipolar depression: focus on relapse prevention studies and the impact of design on generalizability

      • Keming Gao, David E. Kemp, Joseph R. Calabrese
      Pages 159-178

    4. Non-pharmacological somatic treatments for bipolar depression

      • Harold A. Sackeim
      Pages 179-190

    5. Potential novel treatments for bipolar depression

      • Carlos A. Zarate Jr, Husseini K. Manji
      Pages 191-209

  5. Treatment of bipolar disorder in special populations

    1. Front Matter

      Pages 211-211
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    2. Late-onset bipolar disorder

      • John L. Beyer, K. Ranga R. Krishnan
      Pages 213-239

    3. Treatment of childhood-onset bipolar disorder

      • Robert L. Findling
      Pages 241-252

    4. Treatment of bipolar disorder during and after pregnancy

      • Patricia Roy, Jennifer L. Payne
      Pages 253-269
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Keywords

About this book

Although our knowledge of mood disorders is expanding, comparatively little is known about bipolar depression in particular. This book offers the most up-to-date information about the diagnosis, treatment, and research surrounding bipolar depression.

Early chapters provide diagnostic information and review the course, outcome and genetics of this heritable condition. The book gives a thorough and unique overview of the neurobiology of the disorder, including neuroimaging work. Several chapters delineate the treatment of bipolar depression in special populations such as children and pregnant women. Furthermore, the particular issues of suicide, focusing on the need for assessment during both acute and maintenance treatment, are addressed. Finally, acute and long-term treatment strategies for bipolar depression are discussed, including both traditional and novel therapeutics, as well as non-pharmacological treatments.

This volume offers researchers and clinicians key insights into this devastating disorder.

Editors and Affiliations

  • Mood Disorders Research Unit Laboratory of Molecular Pathophysiology, National Institute of Mental Health Mark O. Hatfield Clinical Research Center, Bethesda, USA

    Carlos A. Zarate

  • Laboratory of Molecular Pathophysiology, National Institute of Mental Health Porter Neuroscience Research Center, Bethesda, USA

    Husseini K. Manji

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