Comparative Hepatitis

1. Front Matter

   Pages i-xii

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2. Hepatitis in the clinics — Treatment options

   • Michael P. Manns, Katja Deterding

   Pages 1-20

3. Differential diagnosis of human hepatitis

   • Martin F. Sprinzl, Peter R. Galle

   Pages 21-46

4. Comparative pathology

   • Thomas Longerich, Peter Schirmacher

   Pages 47-73

5. Hepatitis B virus: Lessons learned from the virus life cycle

   • Stephan Urban, Ulrike Protzer

   Pages 75-94

6. Chronic hepatitis C: Portrait of a silent epidemic and the etiologic agent

   • Ralf Bartenschlager, Gang Long, Darius Moradpour

   Pages 95-120

7. Hepatitis A infection

   • Manfred H. Wolff, Axel Schmidt

   Pages 121-134

8. Hepatitis E infection

   • Axel Schmidt, Manfred H. Wolff

   Pages 135-142

9. Bacterial infections of the liver

   • Hilmar Wisplinghoff, Darryn L. Appleton

   Pages 143-160

10. Comparative hepatitis: Diseases caused by adult parasites or their distinct life cycle stages

    • Achim Harder, Heinz Mehlhorn

    Pages 161-216

11. Autoimmune hepatitis in humans

    • Stefan Lüth, Ansgar W. Lohse

    Pages 217-228

12. Hepatitis in dogs

    • Jan Rothuizen

    Pages 229-243

13. Hepatitis in horses

    • Andy E. Durham

    Pages 245-269

14. The woodchuck model of hepadnavirus infection

    • Bud C. Tennant, William E. Hornbuckle, John L. Gerin

    Pages 271-301

15. Hepadnaviruses have a narrow host range — do they?

    • Kai Dallmeier, Michael Nassal

    Pages 303-339

16. The liver as immune escape site for pathogens

    • Percy A. Knolle, Dirk Stabenow

    Pages 341-360

17. Drug candidates for the treatment of viral hepatitis

    • Olaf Weber

    Pages 361-377

18. Back Matter

    Pages 379-383

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Acute and chronic hepatitis and hepatitis-related diseases such as liver failure, liver cirrhosis and hepatocellular carcinoma are among the most important causes for disabilities and death. Hepatocellular injury is due to a variety of agents including viruses, toxins, radiation, injury and drugs but also bacteria, parasites and autoimmune reactions.

This volume reviews today’s knowledge about hepatitis with emphasis on comparative aspects between hepatitis in humans and animals, but also between different etiological agents. This particular viewpoint makes the book relevant for scientists from both human and veterinary medicine, gastroenterologists, pathologists, virologists and students of human and veterinary medicine.

• Hepatitis
• bacteria
• bacterial infection
• bacterial infections
• hepatitis B
• infection
• infections
• liver
• parasite
• viral hepatitis
• virus

From the reviews: “The present volume reviews the most advanced knowledge about hepatitis by comparing this disease in humans and animals and describes the differences between the various etiologic agents. … Overall, this cross disciplinary monograph provides extraordinary up to date information on the latest developments in hepatitis research and covers basic biology and biochemistry of pathogens as well as medical aspects and implications relevant for the general public health. No doubt, the book is an excellent resource for both fundamental research scientist and clinicians.” (Norica Nichita, Romanian Journal of Biochemistry, Vol. 47 (1), 2010)

• Bayer AG, Leverkusen, Germany

  Olaf Weber

• Institute of Virology, Technical University Munich/Helmholtz Center Munich, München, Germany

  Ulrike Protzer

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