Analytical Biotechnology

1. Front Matter

   Pages I-X

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2. Immobilized Biomolecules in Bioanalysis

   • Fritz Pittner

   Pages 1-42

3. Fluorescence Techniques

   • Christian Mayer, Thomas G. M. Schalkhammer

   Pages 43-92

4. Immunoanalytical Methods

   • Franz Gabor, Oskar Hoffmann, Fritz Pittner, Michael Wirth

   Pages 93-133

5. Immunological Strip Tests

   • Ron Verheijen

   Pages 134-166

6. Biosensors

   • Thomas G. M. Schalkhammer

   Pages 167-219

7. Biochips

   • Norbert Stich

   Pages 220-252

8. Nano-clusters and Colloids in Bioanalysis

   • Georg Bauer, Norbert Stich, Thomas G. M. Schalkhammer

   Pages 253-278

9. Atomic Force Microscopy

   • Yilmaz Alguel, Thomas G. M. Schalkhammer

   Pages 279-299

10. Analysis in Complex Biological Fluids

    • Roland Palkovits, Christian Mayer, Thomas G. M. Schalkhammer

    Pages 300-322

11. Back Matter

    Pages 323-331

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Modern analytical biotechnology is focused on the use of a set of enabling platform technologies that provide contemporary, state-of-the-art tools for genomics, proteomics, metabolomics, drug discovery, screening, and analysis of natural product molecules. Thus, analytical biotechnology covers all areas of bioanalysis from biochips and nano-chemistry to biology and high throughput screening. Moreover, it aims to apply advanced automation and micro fabrica­ tion technology to the development of robotic and fluidic devices as well as integrated systems. This book focuses on enhancement technology development by promoting cross-disciplinary approaches directed toward solving key problems in biology and medicine. The scope thus brings under one umbrella many different techniques in allied areas. The purpose is to support and teach the fundamental principles and practical uses of major instrumental techniques. Major platforms are the use of immobilized molecules in biotechnology and bioanalysis, im­ munological techniques, immunological strip tests, fluorescence detection and confocal techniques, optical and electrochemical biosensors, biochips, micro dotting, novel transducers such as nano clusters, atomic force microscopy based techniques and analysis in complex media such as fermentation broth, plasma and serum. Techniques related to HPLC, capillary electrophoresis, gel electrophoresis, and mass spectrometry have not been included in this book but will be covered by further publications. Fundamentals in analytical biotechnology include basic and practical aspects of characterizing and analyzing DNA, proteins, and small metabolites.

• Immunology
• Medical Biotechnology
• Nanobioengineering
• biotechnology (biochips,biosensors)
• biochip
• biochips
• biology
• biomolecule
• biosensor
• biotechnology
• DNA
• fermentation
• fluorescence
• immunology
• microscopy
• natural product
• protein
• proteins
• Proteomics

• TUDELFT, Kluyver Lab. for Biotechnology, BC Delft, The Netherlands

  Thomas G. M. Schalkhammer

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