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Birkhäuser

GABA: Receptors, Transporters and Metabolism

  • Book
  • © 1996

Overview

Editors:
  1. Chikako Tanaka

    1. Hyogo Institute for Aging Brain and Cognitive Disorders, Kobe University, Himeji Hyogo, Japan

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    You can also search for this editor in PubMed   Google Scholar

  2. Norman G. Bowery

    1. The Medical School, University of Birmingham, Edgbaston Birmingham, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Pharmacological Sciences (APS)

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Table of contents (36 chapters)

  1. Front Matter

    Pages I-X
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  3. Glutamate decarboxylase and autoimmunity

    1. Physiological Aspects of GAD-GABA System in the Pancreatic Islet

      • Hiroshi Taniguchi, Junichi Katoh, Motoyoshi Sakaue, Yasuhiro Okada
      Pages 7-12

    2. Membrane Associated L-Glutamate Decarboxylase and Insulin-Dependent Diabetes Mellitus (IDDM)

      • J.-Y. Wu, B. Nathan, C.-C. Hsu, C.-Y. Kuo, G. A. Burghen, R. Wu et al.
      Pages 13-22

    3. Glutamate Decarboxylase, GABA and Autoimmunity

      • Allan J. Tobin, Daniel L. Kaufman
      Pages 23-30

    4. Stiff-Man Syndrome and Glutamic Acid Decarboxylase: An Updated View

      • M. Solimena, R. Dirkx, M. Butler, J.-M. Hermel, J. Guernaccia, K. Marek et al.
      Pages 31-43

    5. Anti-GAD Antibody in Various Neurological Diseases

      • Shigenobu Nakamura, Hidekazu Kamei, Yasuyo Mimori
      Pages 45-52

  4. Molecular structure and functional regulation of GABA transporters

    1. GABA Transporters: Structure, Function and Mechanism

      • Baruch I. Kanner
      Pages 53-61

    2. Heterogeneity of Brain GABA Transporters

      • Kelli E. Smith, Eric L. Gustafson, Laurence A. Borden, T. G. Murali Dhar, Margaret M. Durkin, Pierre J.-J. Vaysse et al.
      Pages 63-72

    3. Developmental Expression of the GABA Transporter GAT4

      • Frantisek Jursky, Nathan Nelson
      Pages 73-82

    4. Functional Regulation of GABA Transporters by PKC and their Distinct Localization

      • Naoaki Saito, Chikako Tanaka
      Pages 83-93

  5. Transmitter release and GABA receptor regulation

    1. GABAB Receptor Control of Transmitter Release in the Spinal Cord

      • H. Teoh, M. Malcangio, N. G. Bowery
      Pages 95-102

    2. Role of GABAA and GABAB Receptors in Ca++ Homeostasis and Transmitter Release in Cerebellar Granule Neurons

      • Arne Schousboe, Lisbeth Elster, Inge Damgaard, Henrik Pallos, Povl Krogsgaard-Larsen, Julianna Kardos
      Pages 103-113

    3. Interactions between Endogenous L-DOPA and GABAA Systems for Cardiovascular Control in the Rat Nucleus Tractus Solitarii

      • Yoshimi Misu, Jin-Liang Yue, Yoko Okumura, Takeaki Miyamae, Yoshio Goshima
      Pages 115-121

    4. Potentiation by Protein Kinase C Activation of GABA Release from Xenopus Oocytes Injected with Rat Brain mRNA

      • Y. Kataoka, S. Kan, S. Mameya, H. Shibaguchi, K. Yamashita, M. Niwa et al.
      Pages 123-127

  6. GABA receptor subtypes and functional regulation

    1. The Molecular Biology of GABAA Receptors and Its Applications

      • Eric A. Barnard
      Pages 129-143

    2. Modelling Functional Domains of the GABAA Receptor Chloride Channel

      • R. W. Olsen, G. B. Smith, S. Srinivasan
      Pages 145-155

    3. GABAA-Receptor Subtypes: Pharmacological Significance and Mutational Analysis in Vivo

      • H. Mohler, J. M. Fritschy, D. Benke, J. Benson, U. Rudolph, B. Lüscher
      Pages 157-171

    4. Regulation of GABAA Receptors by Multiple Protein Kinases

      • Stephen J. Moss, Bernard McDonald, George H. Gorrie, Belinda K. Krishek, Trevor G. Smart
      Pages 173-184

    5. Enhancement of GABA-Induced Current by 20-Hydroxy- Ecdysone in Cultured Cortical Neurons

      • M. Sasa, S. Tsujiyama, K. Ishihara, R. Hanaya, M. Fujita, K. Kurisu et al.
      Pages 185-194
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Keywords

About this book

Highlighting the current developments and future directions in GABA research, the ambitious aim of this topical volume is to cover GABA from the molecular mechanisms of its transmission to new targets for pharmaceutical research. Distinguished scientists at the forefront of GABA research were invited to contribute reviews on glutamate decarboxylase and autoimmunity, molecular structure and functional regulation of GABA transporters, transmitter release and GABA receptor regulation, GABA receptor subtypes and functional regulation, and GABA receptor ligands and their therapeutic application. Describing the latest advances in what has become a rapidly-evolving field, this volume will prove immensely valuable to neuroscientists, pharmacologists, biochemists, and physiologists working in the field of GABA research.

Editors and Affiliations

  • Hyogo Institute for Aging Brain and Cognitive Disorders, Kobe University, Himeji Hyogo, Japan

    Chikako Tanaka

  • The Medical School, University of Birmingham, Edgbaston Birmingham, UK

    Norman G. Bowery

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