Softcover reprint of the original 1st ed. 1994, VII, 210 pp. 13 figs., 1 in color, 21 tabs.
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Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of CD8 genetically deficient (knock-out) mice. In this volume, data for the role that CTL play in human infectious diseases is presented. As such, this represents the first volume in which such information from several different viral and protozoan infections is brought together.
The Role of Cytotoxic T Lymphocytes in Infectious Disease: History, Criteria, and State of the Art.- Therapeutic Reconstitution of Human Viral Immunity by Adoptive Transfer of Cytotoxic T Lymphocyte Clones.- Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Infection: Responses to Structural Proteins.- Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Infection: Regulator Genes.- Cytotoxic T Lymphocytes Specific for Influenza Virus.- Cytotoxic T Lymphocytes in Dengue Virus Infection.- Cytotoxic T Cells in Paramyxovirus Infection of Humans.- Cytotoxic T Cells and Human Herpes Virus Infections.- Cytotoxic T Lymphocyte Responses Against Measles Virus.- The Class I-Restricted Cytotoxic T Lymphocyte Response to Predetermined Epitopes in the Hepatitis B and C Viruses.- Cytotoxic T Lymphocytes in Humans Exposed to Plasmodium falciparum by Immunization or Natural Exposure.