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Marek’s Disease

  • Book
  • © 2001

Overview

Editors:
  1. Kanji Hirai

    1. Department of Tumor Virology, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 255)

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Table of contents (11 chapters)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. The History and Biology of Marek’s Disease Virus

    • P. M. Biggs
    Pages 1-24

  3. Pathogenesis of Marek’s Disease Virus Infection

    • B. W. Calnek
    Pages 25-55

  4. Protective Efficacy of Marek’s Disease Vaccines

    • R. L. Witter
    Pages 57-90

  5. Immune Responses to Marek’s Disease Virus Infection

    • K. A. Schat, C. J. Markowski-Grimsrud
    Pages 91-120

  6. Genetic Resistance to Marek’s Disease

    • L. D. Bacon, H. D. Hunt, H. H. Cheng
    Pages 121-141

  7. The Genomic Structure of Marek’s Disease Virus

    • R. F. Silva, L. F. Lee, G. F. Kutish
    Pages 143-158

  8. Protein-Coding Content of the Sequence of Marek’s Disease Virus Serotype 1

    • B. Lupiani, L. F. Lee, S. M. Reddy
    Pages 159-190

  9. A Complete Genomic DNA Sequence of Marek’s Disease Virus Type 2, Strain HPRS24

    • Y. Izumiya, H.-K. Jang, M. Ono, T. Mikami
    Pages 191-221

  10. Marek’s Disease Virus Latency

    • R. W. Morgan, Q. Xie, J. L. Cantello, A. M. Miles, E. L. Bernberg, J. Kent et al.
    Pages 223-243

  11. Meq: An MDV-Specific bZIP Transactivator with Transforming Properties

    • H.-J. Kung, L. Xia, P. Brunovskis, D. Li, J.-L. Liu, L. F. Lee
    Pages 245-260

  12. Polyvalent Recombinant Marek’s Disease Virus Vaccine Against Poultry Diseases

    • K. Hirai, M. Sakaguchi
    Pages 261-287

  13. Back Matter

    Pages 289-294
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Keywords

About this book

Marek's disease virus (MDV) is a herpesvirus which causes a lymphoproliferative disorder of the domestic chicken worldwide. This serious economical problem caused by MDV was mostly solved by development of an effective vaccine against MDV. The development of live vaccines against the disease is remarkable as it has led to the first example of a commercially available vaccine against cancer as well as against diseases caused by herpesviruses.
This volume gives an overview on many aspects of MDV research and summarizes recent advances in the field. The topics include the history, biology,and molecular biology of MDV, pathogenesis, vaccinal immunity, immune response, genetic resistance and development of recombinant polyvalent vaccines. It is hoped that this volume will make an important contribution towards the control of infectious diseases.

Editors and Affiliations

  • Department of Tumor Virology, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan

    Kanji Hirai

Bibliographic Information

  • Book Title: Marek’s Disease

  • Editors: Kanji Hirai

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-56863-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2001

  • Hardcover ISBN: 978-3-540-67798-7Published: 12 December 2000

  • Softcover ISBN: 978-3-642-63217-4Published: 21 October 2012

  • eBook ISBN: 978-3-642-56863-3Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XI, 296

  • Topics: Virology, Immunology, Molecular Medicine, Cancer Research

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