Logo - springer
Slogan - springer

Biomedical Sciences - Virology | Arenaviruses II - The Molecular Pathogenesis of Arenavirus Infections

Arenaviruses II

The Molecular Pathogenesis of Arenavirus Infections

Oldstone, M.B.A. (Ed.)

Softcover reprint of the original 1st ed. 2002, XVII, 270 p.

Available Formats:
eBook
Information

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.

 
$69.99

(net) price for USA

ISBN 978-3-642-56055-2

digitally watermarked, no DRM

Included Format: PDF

download immediately after purchase


learn more about Springer eBooks

add to marked items

Softcover
Information

Softcover (also known as softback) version.

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.

 
$99.00

(net) price for USA

ISBN 978-3-642-62724-8

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days


add to marked items

Viruses are studied either because they cause significant human, animal or plant disease or because they are useful materials for probing basic phenomena in biology, chemistry, genetics and/or molecular biology. Arenaviruses are unusually interesting in that they occupy both categories. Arenaviruses cause several human diseases known primarily as the hemorrhagic fevers occurring in South and Latin America (Bolivia: Machupo, Argentine, Junin virus, and Brazil: Sabia virus) and in Africa (Lassa fever virus). Because such viruses produce profound disabilities and often kill the persons they infect, they are a source of health concern and economic hardship in the countries where they are prevalent. Further, they provide new problems for healthcare persons owing to the narrowing of the world as visitors from many countries travel increasingly to and from endemic areas and may incubate the infectious agent taking it from an endemic area into an area where the virus is not expected. Such cases are now being re­ corded with increasing frequency. In addition to these hemor­ rhagic fever viruses, the arenavirus lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling and severe than those elicited by the other arenaviruses. Yet, LCMV is of greater concern to non­ arenavirologists and experimentalists using tissue culture or ani­ mals, etc. , because normal-appearing cultured cells or tissues from animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and may transmit that infection to laboratory workers.

Content Level » Research

Keywords » Antibody - Hemorrhagic fever - LCMV - cytokines - immunocytotherapy - lymphocytic choriomeningitis virus - transgenic model

Related subjects » Virology

Table of contents 

List of Contents.- Lymphocytic Choriomeningitis Virus and Immunology.- Innate Immune Responses to LCMV Infections: Natural Killer Cells and Cytokines.- Bystander T Cell Activation and Attrition.- Immunocytotherapy.- Mechanisms of Humoral Immunity Explored Through Studies of LCMV Infection.- Biology and Pathogenesis of Lymphocytic Choriomeningitis Virus Infection.- Contribution of LCMV Transgenic Models to Understanding T Lymphocyte Development, Activation, Tolerance, and Autoimmunity.- Regulation of Virally Induced Autoimmunity and Immunopathology: Contribution of LCMV Transgenic Models to Understanding Autoimmune Insulin-Dependent Diabetes Mellitus.- LCMV and the Central Nervous System: Uncovering Basic Principles of CNS Physiology and Virus-Induced Disease.- Contribution of LCMV Towards Deciphering Biology of Quasispecies in Vivo.- Designing Arenaviral Vaccines.- Junin Virus Vaccines.

Popular Content within this publication 

 

Articles

Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Virology.