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Challenges and Opportunities for Respiratory Syncytial Virus Vaccines

  • Book
  • © 2013

Overview

  • A comprehensive review of the available information on RSV
  • Provides a better understanding of RSV as prerequisite for the development of effective vaccines
  • Written by leading experts in their respective fields
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 372)

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Table of contents (20 chapters)

  1. Virology, Pathogenesis, and Clinical and Epidemiological Features of Disease

  2. Host Response to Infection and Genetics of Disease

  3. Vaccine Platforms and Treatment Options

  4. Animal and Tissue Culture Models of Infection

Keywords

About this book

Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure. The success of RSV immune prophylaxis and the availability of ever more powerful tools to study the immune response and pathogenesis of disease, combined with the ability to construct a wide variety of vaccines using different vaccine platforms, give us grounds to believe that an RSV vaccine is within reach. This book brings together in one source what is currently known about the virus: its clinical and epidemiologic features; the host response and pathogenesis of the disease; vaccines, vaccine platforms, and treatment; and animal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine.

Reviews

From the reviews:

“I enjoyed the book: as an immunologist who has spent 10 years working on RSV there were a number of novel insights and it was nice to see it all in one place. … I will be recommending it to PhD students and Postdocs starting out on RSV research … . also recommend it to people who have been working with RSV for a while to dip in and out of to fill any gaps in the general knowledge.” (John Tregoning, Immunology News, May, 2014)

Editors and Affiliations

  • Department of Pediatrics and Children's Healthcare of Atlanta, Emory University, Atlanta, USA

    Larry J. Anderson

  • Vaccine Research Center, NIH Natl. Inst. of Allergy & Infect. Dis., Bethesda, USA

    Barney S. Graham

Bibliographic Information

  • Book Title: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines

  • Editors: Larry J. Anderson, Barney S. Graham

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-38919-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2013

  • Hardcover ISBN: 978-3-642-38918-4Published: 07 January 2014

  • Softcover ISBN: 978-3-662-52155-7Published: 23 August 2016

  • eBook ISBN: 978-3-642-38919-1Published: 20 December 2013

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XI, 409

  • Number of Illustrations: 16 b/w illustrations, 22 illustrations in colour

  • Topics: Virology, Vaccine, Infectious Diseases, Pneumology/Respiratory System, Pediatrics

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