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Discusses therapeutic potential of biased ligands of G protein-coupled receptors
Describes the molecular mechanisms and therapeutic implications of arrestin-mediated signaling
Discusses the potential of reengineered signaling proteins for gene therapy
This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners.