Springer SmartBook is the new eBook generation. You can read Springer Smartbooks on any smartphone, tablet or laptop/desktop machine. Smartbooks are optimized for Smartphones and Tablets. Find further information on www.springer.com/smartbooks
You can pay for Springer Smartooks with Visa, Mastercard, American Express or Paypal.
After the purchase you can directly access the Smartbook via Online Reader. The access is valid infinitely. For security reasons you need only to login before reading your Smartbook online
price for USA
includes note taking, highlight and search functionality, might contain videos, glossary and quizzes
Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.
You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.
After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.
Written by leading experts in the field of pulmonary hypertension
Broadens your understanding of current, evidence-based pharmacological treatments of various forms of pulmonary hypertension
Comprehensive review of most recent developments in this field including new signaling pathways
This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.
Content Level »Research
Keywords »Vasoactive substances - WHO Group I-V - lung vasculature - pulmonary artery - pulmonary hypertension (PH) - pulmonary vein