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Biomedical Sciences - Pharmacology & Toxicology | Recent Developments in the Regulation of Kinins

Recent Developments in the Regulation of Kinins

Series: Progress in Drug Research, Vol. 69

Sharma, Jagdish N. (Ed.)

2014, IX, 198 p. 17 illus., 7 illus. in color.

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  • Presents recent developments in the regulation of kinins
  • Focuses on the role of the kallikrein-kinin system in various diseases
  • Antagonists/agonists of bradykinin, an important mediator involved in inflammatory conditions, are discussed

This volume presents key topics of current interest with regard to several pathophysiological conditions including (a) the basic and clinical aspects of bradykinin receptor antagonists, (b) the kallikrein-kinin pathways in hypertension and diabetes, (c) tissue kallikrein-kinin therapy for hypertension and organ damage, (d) the renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension, (e) the kallikrein-kinin system in diabetes retinopathy, and (f) genetic manipulation and genetic variation of the kallikrein-kinin system and their impacts on cardiovascular and renal disease. Written by internationally reputed scientists, the book provides an essential overview of the latest developments in the field of kinin research, making it a valuable asset for endocrinologists, nephrologists, cardiologists, pharmacologists, physiologists, ophthalmologists and rheumatologists. Furthermore, it is also intended for postgraduate students in the fields of medicine, pharmacy, physiology and pharmacology, and those working at research organizations.

Content Level » Research

Keywords » Blood pressure - Bradykinin - Inflammatory disorders - Kallikrein-kinin system - Kinin

Related subjects » Human Physiology - Internal Medicine - Pharmacology & Toxicology

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