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Biomedical Sciences - Pharmacology & Toxicology | Treatment and Prevention of Malaria - Antimalarial Drug Chemistry, Action and Use

Treatment and Prevention of Malaria

Antimalarial Drug Chemistry, Action and Use

Staines, Henry M., Krishna, Sanjeev (Eds.)

2012, X, 318 p.

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  • Gives a comprehensive account of the recent advances in anti-malaria drugs
  • Chapters contributed by expert authors
  • Describes new ideas and directions for study

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions.  

Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.

Content Level » Research

Keywords » Antimalarial drugs - Artemisinin - Chemoprophylaxis - Combination therapy - Disease control - Drug resistance - Malaria - Plasmodium

Related subjects » Immunology - Internal Medicine - Medical Microbiology - Pharmacology & Toxicology

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