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Biomedical Sciences - Pharmacology & Toxicology | Molecular Toxicology Protocols

Molecular Toxicology Protocols

Series: Methods in Molecular Biology, Vol. 1105

Keohavong, Phouthone, Grant, Stephen G. (Eds.)

2nd ed. 2014, XV, 646 p. 101 illus., 29 illus. in color.

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Molecular Toxicology Protocols, Second Edition aims to bring together a series of articles describing validated methods to elucidate specific molecular aspects of toxicology, the emphasis being on the application of molecular methods to genetic toxicology. The volume is divided into ten parts, roughly corresponding to the spectrum of biomarkers intermediate between exposure and disease outcomes as proposed in molecular epidemiology models. Subjects of these new chapters range from preparation of fluid specimens for analysis of cellular inflammatory responses to genotoxic insults to sensitive methods for proteomic analysis and aberrant DNA methylation patterns. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Molecular Toxicology Protocols, Second Edition addresses not only the needs of molecular biologists and toxicologists, but also those of individuals interested in applying molecular methods to clinical applications, such as geneticists, pathologists, biochemists, and epidemiologists. 

Content Level » Professional/practitioner

Keywords » DNA adducts - DNA methylation - array technology - gene mutation - toxicoproteomics

Related subjects » Human Genetics - Pharmacology & Toxicology

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