Overview
- Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes
- Highlights differences and similarities between the opioid pharmacology of animals and human
- Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence
- Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications
Part of the book series: Contemporary Neuroscience (CNEURO)
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Table of contents (39 chapters)
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Opioid Antagonists: Chemistry and Pharmacology
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Substance Abuse
Keywords
About this book
Reviews
From the reviews:
“The authors do an excellent job of providing insight into the background of the many factors related to opioid receptor antagonists. … Overall, this work is a well written and interesting text and would be a very useful addition to the personal libraries of those medicinal chemists with a research interest in the modulation of the opioid receptor system.” (Thomas E. Prisinzano, Journal of Medicinal Chemistry, Vol. 53 (2), March, 2010)
“This book is focused on the therapeutic uses of opioid antagonists ranging from classical opioid antagonists to novel chemical entities. In any therapeutic field examined, the aim of book as outlined by the title–‘From Bench to Clinic’–is achieved. … The clinical applications of opioid antagonists are extensively discussed in almost all chapters of this book … . In conclusion, this book gives an interesting analysis of the different fields of knowledge and research concerning therapeutic uses of opioid antagonists in recent years.” (Agostino Marrazzo, ChemBioChem, Vol. 5, 2010)
Editors and Affiliations
Bibliographic Information
Book Title: Opiate Receptors and Antagonists
Book Subtitle: From Bench to Clinic
Editors: Reginald L. Dean, Edward J. Bilsky, S. Stevens Negus
Series Title: Contemporary Neuroscience
DOI: https://doi.org/10.1007/978-1-59745-197-0
Publisher: Humana Totowa, NJ
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2009
Hardcover ISBN: 978-1-58829-881-2Published: 09 March 2009
Softcover ISBN: 978-1-61737-822-5Published: 19 November 2010
eBook ISBN: 978-1-59745-197-0Published: 12 March 2009
Edition Number: 1
Number of Pages: XXIII, 757
Topics: Pharmacology/Toxicology