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  • © 2012

Fundamentals and Applications of Controlled Release Drug Delivery

  • Text easy to understand
  • Book is generously supplemented with diagrams
  • Covers among others mechanisms and modeling of drug delivery, overview of applied therapeutics, and concepts of temporal, spatial and chronotherapeutic approaches to drug delivery
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Delivery Science and Technology (ADST)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xiii
  2. The Value of Drug Delivery

    1. Front Matter

      Pages 1-1
    2. Overview of Controlled Release Mechanisms

      • Ronald A. Siegel, Michael J. Rathbone
      Pages 19-43
  3. Delivery Materials

    1. Front Matter

      Pages 45-45
    2. Hydrophobic Polymers of Pharmaceutical Significance

      • Osama A. Abu-Diak, Gavin P. Andrews, David S. Jones
      Pages 47-73
    3. Hydrogels

      • Hossein Omidian, Kinam Park
      Pages 75-105
    4. Biodegradable Polymers in Drug Delivery Systems

      • Jamie Tsung, Diane J. Burgess
      Pages 107-123
  4. Temporal Delivery Systems and Mechanisms

    1. Front Matter

      Pages 125-125
    2. Diffusion Controlled Drug Delivery Systems

      • Juergen Siepmann, Ronald A. Siegel, Florence Siepmann
      Pages 127-152
    3. Swelling Controlled Drug Delivery Systems

      • Juergen Siepmann, Florence Siepmann
      Pages 153-170
    4. Degradable Polymeric Carriers for Parenteral Controlled Drug Delivery

      • C. Wischke, S. P. Schwendeman
      Pages 171-228
    5. Porous Systems

      • Ronald A. Siegel
      Pages 229-251
  5. Spatial Delivery Systems and Mechanisms

    1. Front Matter

      Pages 253-253
    2. Targeted Delivery Using Biodegradable Polymeric Nanoparticles

      • Elias Fattal, Hervé Hillaireau, Simona Mura, Julien Nicolas, Nicolas Tsapis
      Pages 255-288
    3. Liposomes in Drug Delivery

      • Vladimir Torchilin
      Pages 289-328
  6. Applications

    1. Front Matter

      Pages 357-357
    2. Biological Rhythms, Drug Delivery, and Chronotherapeutics

      • Michael H. Smolensky, Ronald A. Siegel, Erhard Haus, Ramon Hermida, Francesco Portaluppi
      Pages 359-443
    3. Site Specific Controlled Release for Cardiovascular Disease: Translational Directions

      • Ilia Fishbein, Michael Chorny, Ivan S. Alferiev, Robert J. Levy
      Pages 445-492

About this book

This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.

Editors and Affiliations

  • Phalempin, France

    Juergen Siepmann

  • , Department of Pharmaceutics, University of Minnesota, Minneapolis, USA

    Ronald A. Siegel

  • , School of Pharmacy, Griffith University, Southport, Australia

    Michael J. Rathbone

About the editors

Professor Juergen Siepmann is Professor of Pharmaceutics at the College of Pharmacy, Université Lille Nord de France, Lille, France. He studied pharmacy and received his doctoral degree from the Freie Universitaet Berlin, Berlin, Germany, in 1999. His research focuses on the elucidation of the underlying mass transport phenomena in controlled drug delivery systems. Prof. Siepmann is reviews editor of the International Journal of Pharmaceutics and president of APGI (French Association of Pharmaceutical Technology). Since 2010 he is heading the INSERM (French National Institute of Health and Medical Research) research group “Controlled Drug Delivery Systems and Biomaterials”.

 

 

Ronald A. Siegel, Sc.D., is Professor of Pharmaceutics and Biomedical Engineering at the University of Minnesota.  He received his doctoral degree from MIT under the direction of Prof. Robert Langer in 1984, and taught at the University of California, San Francisco until 1998, when he moved to Minnesota.  Professor Siegel is Fellow of the Controlled Release Society (CRS), the American Association of Pharmaceutical Scientists, and the American Institute of Medical and Biological Engineering.  He was president of CRS from 1997-1998.  His present research interests include hydrogels, block polymers, microfabricated sensors and drug delivery systems, and mathematical modeling of transport.

 

 

Michael J. Rathbone is Associate Professor of Pharmaceutics at the School of Pharmacy, Griffith University, Australia.  Dr. Rathbone’s research interests are in the modified delivery of bioactives to the mouth, polymeric delivery systems and long acting veterinary drug delivery systems.  He is a Fellow of the Controlled Release Society (CRS) and received the CRS Distinguished Service Award in 2006.  He has edited or co-edited many books in the fields of modified release drug delivery, oral mucosal drug delivery andveterinary drug delivery.

Bibliographic Information

  • Book Title: Fundamentals and Applications of Controlled Release Drug Delivery

  • Editors: Juergen Siepmann, Ronald A. Siegel, Michael J. Rathbone

  • Series Title: Advances in Delivery Science and Technology

  • DOI: https://doi.org/10.1007/978-1-4614-0881-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012

  • Hardcover ISBN: 978-1-4614-0880-2Published: 14 December 2011

  • Softcover ISBN: 978-1-4899-8646-7Published: 03 March 2014

  • eBook ISBN: 978-1-4614-0881-9Published: 15 December 2011

  • Series ISSN: 2192-6204

  • Series E-ISSN: 2192-6212

  • Edition Number: 1

  • Number of Pages: XIV, 594

  • Topics: Pharmacology/Toxicology, Biochemistry, general, Pharmacy

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access