Skip to main content
  • Book
  • © 2014

Pharma-Nutrition

An Overview

  • Reviews the impact and effects of natural products and functional/medical foods (nutritional programming) on disease management, specifically focusing on diseases related to inflammation and immunity, cancer, COPD, cachexia, allergy and cognitive disorders
  • Highlights the molecular characteristics of food ingredients towards clinical effectiveness and relevance
  • Stresses the importance of a multi-target approach versus a single-target approach
  • Includes supplementary material: sn.pub/extras

Part of the book series: AAPS Advances in the Pharmaceutical Sciences Series (AAPS, volume 12)

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (23 chapters)

  1. Front Matter

    Pages i-xv
  2. General

    1. Front Matter

      Pages 1-1
    2. Pharma-Nutrition

      • Seil Sagar, Gert Folkerts, Johan Garssen
      Pages 3-8
    3. New Developments in Food Safety Assessment: Innovations in Food Allergy and Toxicological Safety Assessment

      • Geert Houben, Marty Blom, Jolanda van Bilsen, Lisette Krul
      Pages 9-27
    4. Bridging a Pharma-Like Innovation Gap in Medical Nutrition

      • Tamar C. Weenen, Kenneth Fernald, Esther S. Pronker, Harry Commandeur, Eric Claassen
      Pages 29-52
  3. Inflammation and Immunity

    1. Front Matter

      Pages 53-53
    2. Modulation of the Gut Ecosystem in Irritable Bowel Syndrome

      • Julia König, Robert-Jan Brummer
      Pages 55-73
    3. Role of Omega-6 and Omega-3 Fatty Acids in Inflammatory Bowel Disease

      • Kevan Jacobson, Philip C. Calder
      Pages 75-89
    4. N-3 Polyunsaturated Fatty Acid and Neuroinflammation in Aging: Role in Cognition

      • Sophie Layé, Charlotte Madore, Jean-Christophe Delpech, Corinne Joffre, Agnès Nadjar
      Pages 91-112
    5. Effects of Natural Products on Pharmacokinetics and Pharmacodynamics of Drugs

      • Shizuo Yamada, Shingen Misaka, Yoshihiko Ito, Hiroshi Watanabe, Keizo Umegaki
      Pages 189-211
    6. Nutrition and Gastrointestinal Health as Modulators of Parkinson’s Disease

      • Heather E. Rasmussen, Bryana R. Piazza, Christopher B. Forsyth, Ali Keshavarzian
      Pages 213-242
    7. Eat to Heal: Natural Inducers of the Heme Oxygenase-1 System

      • Matheus Correa-Costa, Leo E. Otterbein
      Pages 243-256
  4. Cancer and Cachexia

    1. Front Matter

      Pages 257-257
    2. Recent Developments in Treatment of Cachexia

      • Josep M. Argilés, Francisco Javier López-Soriano, Britta Stemmler, Sílvia Busquets
      Pages 259-273
    3. Nutrition in Oncology: From Treating Cachexia to Targeting the Tumor

      • Alessandro Laviano, Chiara Gori, Martina Stronati, Alessia Mari, Serena Rianda
      Pages 295-304

About this book

Natural products and functional/medical foods are now widely acknowledged as having an effect on the microbiome of the intestine, which in turn influences the outcome of certain disease. This book reviews the impact and effects of natural products and functional/medical foods (nutritional programming) on disease management, specifically focusing on diseases related to 1) Inflammation and Immunity, 2) Cancer, COPD and Cachexia, 3) Allergy and 4) Brain Neuro/Immune. Hippocrates said "let medicine be thy food and food be thy medicine". While most of us are familiar with Hippocrates famous words, we admit that in recent times, the disciplines of pharma and nutrition have evolved separately. Today, with the ever growing burden of diseases in modern society, we see a convergence of the two in relation to specific disease prevention and treatment. This re-discovered common ground between the complementary values of pharma and nutrition can be conceptualized in the term pharma-nutrition. Various chapters in the book review the aspects of molecular characteristics of food ingredients towards clinical effectiveness and relevance.

Editors and Affiliations

  • Pharmacology, Utrecht University, The Netherlands

    Gert Folkerts

  • Immunopharmacology, Utrecht University, The Netherlands

    Johan Garssen

About the editors

Dr. G. Folkerts started his career in the Rudolf Magnus Institute for Pharmacology at the Utrecht University. He did his thesis on viral infections and asthma and is appointed as full professor (Chair COPD and In Vivo Pharmacology) in the division of Pharmacology, Department of Pharmacy, Faculty of Sciences. He spent some time at the University of Edmonton (Canada), the Wellcome Research Institute in Beckenham (UK) and Janssen Research Foundation in Beerse (Belgium). He has successfully guided a great number of research projects concerning inflammatory diseases. These activities have resulted in more than 160 scientific publications in well-respected international journals. He is a full-time professor at the Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands. He is also an associated editor of The European Journal of Pharmacology and is CEO of the contract research company Curax BV.

Dr. Johan Garssen studied medicine and biology at the Free University, Amsterdam, the Netherlands. He specialized in immunology and pharmacology. He completed his PhD thesis at the University of Utrecht on the role of T cells in respiratory allergy, an immunopharmacological approach. This PhD program was partly performed at Yale University, New Haven, USA. After a postdoc period, he became senior scientist at the National Institute of Public Health in the Netherlands. There he coached many research projects, both preclinical as well as clinical research, in the field of immunomodulation induced by a.o. nutritional ingredients, drugs and environmental agents. He became head of the immunology section at Numico-Research, Wageningen, the Netherlands and director of the immunology platform of Nutricia Research (formerly Numico and Danone), medical nutrition and infant nutrition. He now is a full professor in immunopharmacology at the Utrecht Institute for Pharmaceutical Sciences, Utrecht University and has been nominated University Profiling Professor Immunopharmacology. Additionally, he has published more than 370 peer reviewed papers in the field of immunomodulation.

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access