Editors:
- Supports the development of innovative cancer treatments through ADC techniques
- Provides step-by-step methodologies that are readily reproducible
- Features expert tips and key implementation advice to ensure successful results
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1045)
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Table of contents (20 protocols)
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Front Matter
About this book
Antibody-drug conjugates (ADCs) represent a promising therapeutic approach for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs. In Antibody-Drug Conjugates, expert researchers provide detailed protocols for many of the key ADC techniques necessary for working in the field. These chapters and methodologies are aimed at the key tasks necessary to identify a suitable target, properly design the mAb, the linker and the payload, as well as to conjugate them in a reproducible and scalable fashion. Written in the highly successful Methods in Molecular Biology™ format, these detailed chapters include the kind of practical implementation advice that guarantees quality results.
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Authoritative and timely, Antibody-Drug Conjugates aims to further drive ADC development and thus help toward improving cancer treatments of the future.Editors and Affiliations
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Lonza Ltd, Visp, Switzerland
Laurent Ducry
Bibliographic Information
Book Title: Antibody-Drug Conjugates
Editors: Laurent Ducry
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-541-5
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2013
Hardcover ISBN: 978-1-62703-540-8Published: 03 August 2013
Softcover ISBN: 978-1-4939-6026-2Published: 23 August 2016
eBook ISBN: 978-1-62703-541-5Published: 04 August 2013
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: X, 317
Number of Illustrations: 54 b/w illustrations, 42 illustrations in colour
Topics: Pharmacology/Toxicology, Oncology