Overview
Enriches understanding of brain disorders by considering the world outside the brain
Reviews changes of the conceptual framework of neurodegenerative disorders
Discusses new therapeutic strategies for neurodegenerative disorders
Equips readers to understand the paradigm shift of neurodegenerative disorders
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Table of contents (13 chapters)
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Front Matter
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A New Concept of Neurodegeneration in Biology and Pathophysiology
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Front Matter
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Changes in Clinical Evaluation and New Biomarkers
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Front Matter
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Risk Factors in Neurodegeneration
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Front Matter
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Future Directions for Therapy
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Front Matter
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Health Promotion: Prevention and Quality of Life
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Front Matter
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Keywords
About this book
This book sheds new light on neurodegenerative disorders as systemic diseases. Classically, neuronal cell death was a hallmark of such disorders. However, it has become evident that neural dysfunction is more important in the pathophysiology of neurodegenerative disorders. More recently, the prionoid-spreading hypothesis of disease-causing molecules has attracted a great deal of attention. Therapeutic strategies thus must be reconsidered in the light that neurodegenerative disorders are indeed systemic diseases. The first part of this book introduces the concept of neurodegeneration in biology and pathophysiology. The second part focuses on clinical evaluation and biomarkers from the perspective of this new concept, while the third summarizes the risk factors of neurodegeneration. The fourth part of this work indicates future directions of treatment, and the final part discusses health promotion for prevention and quality of life. This book will be of interest to both researchers and medical personnel, and provides a fresh approach to neurodegenerative diseases, paving the way to new research and improved quality of health care for patients.
Editors and Affiliations
Bibliographic Information
Book Title: Neurodegenerative Disorders as Systemic Diseases
Editors: Keiji Wada
DOI: https://doi.org/10.1007/978-4-431-54541-5
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Japan 2015
Hardcover ISBN: 978-4-431-54540-8Published: 30 October 2015
Softcover ISBN: 978-4-431-56298-6Published: 23 August 2016
eBook ISBN: 978-4-431-54541-5Published: 21 October 2015
Edition Number: 1
Number of Pages: VIII, 304
Topics: Neurosciences, Neurology, Psychiatry, Neurobiology