Phospholipids and Signal Transmission

1. Front Matter

   Pages I-XII

   PDF

2. Glycosylphosphatidylinositol Anchored Recognition Molecules That Mediate Intercellular Adhesion and Promote Neurite Outgrowth

   • Patrick Doherty, Frank S. Walsh

   Pages 1-11

3. Lipid Synthesis and Targeting to the Mammalian Cell Surface

   • Alex Sandra, Wouter van’t Hof, Ida van Genderen, Gerrit van Meer

   Pages 13-37

4. The Aminophospholipid Transporter from Human Red Blood Cells

   • Peter E. Coderre, Alan J. Schroit

   Pages 39-48

5. Lipids (Composition and Topography) in Adrenal Chromaffin Granules and Their Relevance for the Function of These Organelles

   • H. Winkler

   Pages 49-59

6. Accelerated Cell Membrane Degradation in Alzheimer’s Disease Brain: Relationship to Amyloid Formation?

   • Roger M. Nitsch, Barbara E. Slack, John H. Growdon, Richard J. Wurtman

   Pages 61-69

7. Mechanistic and Functional Aspects of Oscillatory Calcium Signalling

   • Andrew P. Thomas, Thomas A. Rooney, Dominique C. Renard

   Pages 71-86

8. Phospholipid Hydrolysis and [Ca2+]i Control

   • J. Meldolesi, G. Gatti, M. Magni, E. Clementi, D. Zacchetti, H. Scheer

   Pages 87-93

9. Phosphoinositide Hydrolysis Indicates Functional Receptors in Astrocytes and in Neoplastic Cells from the Human CNS

   • S. Murphy, G. Bruner, M. L. Simmons

   Pages 95-105

10. The G-Proteins Regulating Phosphoinositide Breakdown

    • J. H. Exton, S. J. Taylor, J. L. Blank

    Pages 107-113

11. Actions and Interactions of Cholinergic and Excitatory Aminoacid Receptors on Phosphoinositide Signals, Excitotoxicity and Neuroplasticity

    • Pawels Kurian, Fulton T. Crews, L. Judson Chandler, Norbert J. Pontzer

    Pages 115-121

12. The Phospholipid Environment of Activated Synaptic Membrane Receptors May Provide Both Intracellularly and Retrogradely Acting Signals for the Regulation of Neuro(Muscular) Transmission

    • E. Heilbronn, L. Järlebark

    Pages 123-133

13. The Role of Arachidonic Acid as a Retrograde Messenger in Long-Term Potentiation

    • M. A. Lynch, K. L. Voss, M. P. Clements, T. V. P. Bliss

    Pages 135-149

14. Resisting Memory Storage: Activating Endogenous Protein Kinease C Inhibitors

    • Aryeh Routtenberg

    Pages 151-162

15. B-50 Phosphorylation in Response to Different Patterns of Electrical Stimulation in Rat Hippocampal Slices

    • R. Corradetti, Maria Grazia Nunzi, Willem Hendrick Gispen, Cristina Gianotti

    Pages 163-170

16. Participation of Inositol Phosphates, Protein Kinase C, G-Proteins and Cyclic AMP in Signal Transduction in Primary Rat Astroglial Cultures

    • G. Hertting, P. Gebicke-Haerter, A. Seregi

    Pages 171-187

17. Sphingosine, a Breakdown Product of Cellular Sphingolipids, in Cellular Proliferation and Phospholipid Metabolism

    • Sarah Spiegel

    Pages 189-203

18. Regulation of Phosphatidylserine Synthesis during T Cell Activation

    • Claude Aussel

    Pages 205-218

19. Anti-Phosphatidylserine Monoclonal Antibody: Structural Template for Studying Lipid-Protein Interactions and for Identificationo of Phosphatidylserine Binding Proteins

    • Masato Umeda, Koji Igarashi, Shigeru Tokita, Farooq Reza, Keizo Inoue

    Pages 219-234

20. Immunomodulation by Serine Phospholipids

    • A. Bruni, F. Bellini, E. Caselli, G. Monastra, D. Ponzin

    Pages 235-247

Once Nietzsche said that human beings may be divided into two categories: Apollonians and Dionysians*. By this the philosopher meant that there are human beings a) who know what they are going to do in the long-term future (what we now call the grant application for the next 5 years), i. e. , Apollonians, and b) who barely know what they are going to do tomorrow morning before breakfast, i. e. , Dionysians. ** To organize a symposium, this symposium in particular, a committee had to be formed either of individuals sharing both Nietzschean characteristics or of individuals possessing either characteristic. Considering the rarity of the former type of subject, this organizing committee was spontaneously formed by a typical sample of both types of individuals. We first met in Perugia in 1988. Those of us who were Apollonians had thus a chance to organize a programme. The Dionysians knew what was going to happen to them, but, of course, did not know yet how to cope with it. They duly did so every day of the meeting, after breakfast. The organizers decided that it would be a useful exercise to assemble experts having different perspectives but all pursuing a very rapidly developing aspect of cell biology. They also hoped that these selected Apollonians and Dionysians would not merely recount their results but try to project the future through active interchanges of ideas and opinions with other attendees.

• Activation
• Calcium
• Lipid
• Phosphoinositide
• Phosphoinositides
• Phospholipide
• Phospholipids
• Signal Transmission
• Signalübertragung
• Sphingolipide
• Sphingolipids
• metabolism

• CNRS, Centre de Neurochimie, Strasbourg, France

  Raphaël Massarelli

• Department of Medical Biochemistry, College of Medicine, The Ohio State University, Columbus, USA

  Lloyd A. Horrocks

• Department of Biochemistry and Molecular Biology, The University of Manitoba, Winnipeg, Canada

  Julian N. Kanfer

• Department of Pharmacology, University of Mainz, Mainz, Germany

  Konrad Löffelholz

Policies and ethics