Softcover reprint of the original 1st ed. 1997, VII, 198 pp. 43 figs. some in color, 5 tabs.
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Understanding the developmental origin of the nervous system is important for two reasons. This knowledge, first, is intellectually interesting since it provides an example of the assembly of a multicellular system, and second, will enable us to control the assembly and disassembly of this system in health and disease. This volume summarizes the current knowledge regarding the CNS stem cells which give rise to the nervous system.
Stem Cells: The Lessons from Hematopoiesis.- NRSF: A Coordinate Repressor of Neuron-Specific Genes Expressed in CNS Neural Progenitor Cells.- Segregation of Cell Lineage in the Avian Neural Crest.- Comparative Strategies of Subependymal Neurogenesis in the Adult Forebrain.- Characterization of Neuronal Progenitor Cells of the Neonatal Forebrain.- Neurogenesis in the Adult Brain: Prospects for Brain Repair.- The Oligodendrocyte-Type-2 Astrocyte Lineage: In vitro and in vivo Studies on Development, Tissue Repair and Neoplasia.- Neurogenesis in the Adult Brain: Lessons Learned from the Studies of Progenitor Cells from the Embryonic and Adult Central Nervous Systems.- Use of Conditionally Immortalized Neural Progenitors for Transplantation and Gene Transfer to the CNS.- The Origins of the Central Nervous System.- Transplantation and Differentiation of Neural “Stem-Like” Cells: Possible Insights into Development and Therapeutic Potential.